SCHEMBL502238

SCHEMBL502238

CCCCCC(C)(C)c1ccc(Nc2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 17/20 0.50
CNR1 P21554 7/20 0.41
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39060 0.95 CNR2 (0.54) CNR2CNR1
SCHEMBL501958 0.88 CNR2 (0.49) CNR2CNR1HDAC3HDAC1HDAC2
SCHEMBL6927738 0.85 CNR2 (0.47) CNR2
SCHEMBL30108338 0.83 MAPT (0.46) CNR2CNR1HDAC3HDAC1HDAC2
SCHEMBL501783 0.82 CNR2 (0.45) CNR2CNR1
SCHEMBL502028 0.82 CNR2 (0.42) CNR2CNR1
SCHEMBL6932062 0.82 CNR2 (0.43) CNR2CNR1
SCHEMBL8962086 0.81 ALDH1A1 (0.50) CNR2CNR1
SCHEMBL25888283 0.80 NPC1 (0.43) HDAC3HDAC8HDAC6
SCHEMBL3356610 0.79 ALDH1A1 (0.49) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396256-A1 STABILIZER COMBINATION FOR PREVENTING DEGRADATION OF SYNTHETIC POLYMERS BASF SE (DE) 2024-07-10 EP claimed
WO-2023030859-A1 STABILIZER COMBINATION FOR PREVENTING DEGRADATION OF SYNTHETIC POLYMERS BASF SE (DE) 2023-03-09 WO claimed
EP-1249845-B1 Stabilized medium and high voltage cable insulation composition BASF SE (DE) 2012-07-11 EP claimed
US-7056967-B2 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-06-06 US claimed
US-20020198344-A1 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US claimed
EP-1249845-A2 Stabilized medium and high voltage cable insulation composition Ciba SC Holding AG (CH) 2002-10-16 EP claimed
US-5869565-A INCLUDES A BENZOFURANONE DERIVATIVE, A PHENOLIC ANTIOXIDANT AND AN AMINO ANTIOXIDANT OF THE SECONDARY AMINE TYPE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-02-09 US claimed
EP-0674615-B1 DECOLORIZATION OF ALKYLATED DIARYLAMINES GOODRICH CO B F (US) 1997-06-04 EP claimed
EP-0475904-B1 Mixtures and compositions containing phenothiazines CIBA GEIGY AG (CH) 1997-01-15 EP claimed
EP-0432089-B1 Lubricating oil compositions CIBA GEIGY AG (CH) 1996-09-04 EP claimed
US-5262072-A Stabilization of a lubricant or hydraulic fluid against oxidation and/or heat degradation CIBA-GEIGY CORPORATION (US) 1993-11-16 US claimed
US-5167844-A Stabilized against thermal and oxidative degradation CIBA-GEIGY CORPORATION (US) 1992-12-01 US claimed
EP-0346283-B1 LUBRICANT COMPOSITION CIBA-GEIGY AG (CH) 1992-07-29 EP claimed
EP-0480875-A1 Lubricating composition CIBA-GEIGY AG (CH) 1992-04-15 EP claimed
US-5091099-A Phosphite-free; containing aromatic amines and substituted phenols CIBA-GEIGY CORPORATION (US) 1992-02-25 US claimed
EP-0432089-A1 Lubricating oil compositions CIBA-GEIGY AG (CH) 1991-06-12 EP claimed
EP-0398215-A1 Lubricant compositions CIBA-GEIGY AG (CH) 1990-11-22 EP claimed
US-4963276-A MIXTURE OF AROMATIC AMINE AND ORGANOSULFUR COMPOUND CIBA-GEIGY CORPORATION (US) 1990-10-16 US claimed
EP-0346283-A2 Lubricant composition CIBA-GEIGY AG (CH) 1989-12-13 EP claimed
EP-0323403-A2 Lubricant composition CIBA-GEIGY AG (CH) 1989-07-05 EP claimed