SCHEMBL6932062

SCHEMBL6932062

CCCCCC(C)(C)c1ccc(Nc2ccc(CCc3ccccc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 8/20 0.43
SIGMAR1 Q99720 2/20 0.43
CNR1 P21554 5/20 0.40
TRPV1 Q8NER1 1/20 0.40
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MAPT P10636 2/20 0.39
GPR55 Q9Y2T6 2/20 0.38
GPR18 Q14330 1/20 0.38
EBP Q15125 1/20 0.38
HPGD P15428 1/20 0.38
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6927738 0.90 CNR2 (0.47) CNR2MAPTHPGDMEN1ALDH1A1
SCHEMBL501958 0.90 CNR2 (0.49) CNR2CNR1MAPTHPGDMEN1
SCHEMBL39060 0.86 CNR2 (0.54) CNR2CNR1
SCHEMBL30108338 0.85 MAPT (0.46) CNR2CNR1MAPTHPGDMEN1
SCHEMBL502238 0.82 CNR2 (0.50) CNR2CNR1
SCHEMBL8962086 0.79 ALDH1A1 (0.50) CNR2CNR1HPGDALDH1A1SMN1; SMN2
SCHEMBL6931652 0.78 RAB9A (0.51) CNR1ALDH1A1MAPK1
SCHEMBL3356610 0.78 ALDH1A1 (0.49) CNR2CNR1HPGDALDH1A1SMN1; SMN2
SCHEMBL399240 0.78 CNR2 (0.54) CNR2CNR1
SCHEMBL9453768 0.78 CNR2 (0.54) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1023377-B1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEM CO INC (US) 2003-12-03 EP claimed
US-6348514-B1 ISOCYANATE REACTIVE COMPOSITION WITH STABILIZER OF METHYL 3-(4-HYDROXY-3,5-DI-TERT-BUTYLPHENYL)PROPIONATE UNIROYAL CHEMICAL COMPANY, INC. 2002-02-19 US claimed
EP-1023377-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 2000-08-02 EP claimed
WO-1999016821-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
EP-0691997-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-17 EP claimed
WO-1994021722-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-29 WO claimed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US claimed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US claimed
US-5571453-A PHOTOSTABILITY USING REACTION PRODUCT OF DIPHENYLAMINE, ISOBUTYLENE AND DIISOBUTYLENE AND STERICALLY HINDERED PHENOL AND TRIHYDROCARBYL PHOSPHITE UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-11-05 US disclosed
EP-0691997-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-17 EP disclosed
WO-1994021722-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-29 WO disclosed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US disclosed
EP-0399142-B1 Stabilizer compositions for polyols and polyurethane foam VANDERBILT CO R T (US) 1994-01-26 EP disclosed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US disclosed
EP-0556612-A1 Synergistic stabilizer compositions for polyols and polyurethane foam R.T. VANDERBILT COMPANY, Inc. (US) 1993-08-25 EP disclosed
US-5156762-A 2,6-Di-tert-butyl-4-sec-butylphenol, phenothiazine or alkyl-substitued derivative, and reaction product of styrene, diisobutylene and diphenylamine R. T. VANDERBILT COMPANY, INC. (US) 1992-10-20 US disclosed
US-5143943-A 2,6-di-tert-butyl-4-sec-butylphenol; reaction product of styrene, diphenylamine, and diisobutylene; and phenothiazine compound; discoloration inhibition R. T. VANDERBILT COMPANY, INC. (US) 1992-09-01 US disclosed
EP-0399142-A2 Stabilizer compositions for polyols and polyurethane foam R.T. VANDERBILT COMPANY, INC. (US) 1990-11-28 EP disclosed
US-4933374-A 2,6-DI-TERT-BUTYL-4-SEC-BUTYLPHENOL, REACTION PRODUCT OF DIISOBUTYLENE, STYRENE AND DIPHENYLAMINE R. T. VANDERBILT COMPANY, INC. (US) 1990-06-12 US disclosed