SCHEMBL6928086

SCHEMBL6928086

C[C@@H](O)C(C#N)C(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSS P25774 11/20 0.53
CTSL P07711 9/20 0.53
ALDH1A1 P00352 3/20 0.50
CTSB P07858 6/20 0.47
CTSK P43235 6/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPK1 P28482 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
TACR1 P25103 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6928091 1.00 CTSS (0.53) CTSSCTSLALDH1A1CTSBCTSK
SCHEMBL6928082 1.00 CTSS (0.53) CTSSCTSLALDH1A1CTSBCTSK
SCHEMBL19866499 0.82 ALDH1A1 (0.55) CTSSCTSLALDH1A1CTSBCTSK
SCHEMBL10523992 0.82 ALDH1A1 (0.55) CTSSCTSLALDH1A1CTSBCTSK
SCHEMBL13814378 0.78 ALDH1A1 (0.58) CTSSCTSLALDH1A1CTSBCTSK
SCHEMBL21843047 0.78 ALDH1A1 (0.58) CTSSCTSLALDH1A1CTSBL3MBTL1
SCHEMBL12189627 0.78 ALDH1A1 (0.58) CTSSCTSLALDH1A1CTSBCTSK
SCHEMBL20622938 0.78 ALDH1A1 (0.58) CTSSCTSLALDH1A1CTSBCTSK
SCHEMBL17384657 0.78 ALDH1A1 (0.58) CTSSCTSLALDH1A1CTSBL3MBTL1
SCHEMBL1107604 0.78 ALDH1A1 (0.62) CTSSCTSLALDH1A1CTSBCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6586616-B1 Cyanation and esterification of 3,4-epoxybutyric acid sodium salts to form chemical intermediates for antilipemic agents; by-product inhibition SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2003-07-01 US disclosed
EP-1149068-A4 A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER SAMSUNG FINE CHEMICALS CO LTD (KR) 2003-01-02 EP disclosed
EP-1149068-A1 A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER Samsung Fine Chemicals Co., Ltd. (KR) 2001-10-31 EP disclosed
WO-2000046186-A1 A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER SAMSUNG FINE CHEMICALS CO., LTD (KR) 2000-08-10 WO disclosed