Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 12/20 | 0.50 |
| ▸ | CTSL | P07711 | 10/20 | 0.50 |
| ▸ | CTSB | P07858 | 7/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10523992 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CTSSCTSLCTSBCTSK | |
| SCHEMBL6960308 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CTSSCTSLCTSBCTSK | |
| SCHEMBL14046783 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CTSSCTSLCTSBCTSK | |
| SCHEMBL6928082 | 0.82 | CTSS (0.53) | ALDH1A1CTSSCTSLCTSBCTSK | |
| SCHEMBL6928086 | 0.82 | CTSS (0.53) | ALDH1A1CTSSCTSLCTSBCTSK | |
| SCHEMBL6928091 | 0.82 | CTSS (0.53) | ALDH1A1CTSSCTSLCTSBCTSK | |
| SCHEMBL20921123 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CTSSCTSLCTSBCTSK | |
| SCHEMBL28642241 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CTSSCTSLCTSBCTSK | |
| SCHEMBL17005822 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CTSSCTSLCTSBCTSK | |
| SCHEMBL27314350 | 0.80 | ALDH1A1 (0.51) | ALDH1A1CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370401-B2 | Substituted nucleosides, nucleotides and analogs thereof | Janssen Biopharma, Inc. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20190031703-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Biopharma, Inc. | 2019-01-31 | — | — | US | disclosed |
| US-20180044369-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Biopharma, Inc. | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044369-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NT5C3B, NUDT1 | ALDH1A1 2525/4885CTSS 3492/4885CTSL 2567/4885 |
| US-10370401-B2 | Substituted nucleosides, nucleotides and analogs thereof | PNP, NT5C3B, NUDT1 | ALDH1A1 2525/4885CTSS 3492/4885CTSL 2567/4885 |
| US-20190031703-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NUDT1, NT5C2 | ALDH1A1 1431/4885CTSS 2963/4885CTSL 2235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.