SCHEMBL69281

SCHEMBL69281

Oc1cc(Cl)c(Cl)c(Cc2cc(O)cc(Cl)c2Cl)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.62
HPGD P15428 7/20 0.62
CYP3A4 P08684 6/20 0.62
CRHBP P24387 1/20 0.62
CRHR2 Q13324 1/20 0.62
TSHR P16473 5/20 0.43
HSP90AA1 P07900 4/20 0.43
ALOX15 P16050 3/20 0.43
CHRM1 P11229 2/20 0.43
TBXA2R P21731 2/20 0.43
MAPK1 P28482 2/20 0.43
ADRA1A P35348 2/20 0.43
HTR2B P41595 2/20 0.43
MEN1 O00255 2/20 0.43
USP2 O75604 2/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 2/20 0.43
HSPD1 P10809 2/20 0.43
HSPA5 P11021 2/20 0.43
ALOX12 P18054 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20180974 0.81 HSD17B10 (0.56) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL330705 0.78 HSD17B10 (1.00) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL7994963 0.72 PTGS2 (0.53) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL7994866 0.72 PTGS2 (0.53) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL7995859 0.72 PTGS2 (0.53) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL7992788 0.72 PTGS2 (0.53) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL7995041 0.72 PTGS2 (0.53) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL7785639 0.70 HSD17B10 (0.72) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL9150760 0.70 HSD17B10 (0.55) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL6166403 0.70 HSD17B10 (0.56) HSD17B10HPGDCYP3A4CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 HSD17B10 2777/4885HPGD 3275/4885CYP3A4 2028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.