SCHEMBL6166403

SCHEMBL6166403

Oc1ccc(Cc2ccc(O)cc2Cl)c(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.56
MEN1 O00255 2/20 0.48
MAPT P10636 2/20 0.48
KMT2A Q03164 2/20 0.48
TTR P02766 1/20 0.48
TYR P14679 1/20 0.46
ESR1 P03372 6/20 0.45
ESR2 Q92731 4/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CYP3A4 P08684 2/20 0.43
HPGD P15428 2/20 0.43
SLC22A1 O15245 1/20 0.43
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
HSP90AA1 P07900 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10767990 0.89 HSD17B10 (0.46) HSD17B10MEN1MAPTKMT2AHSP90AA1
SCHEMBL10764611 0.86 MEN1 (0.61) HSD17B10MEN1MAPTKMT2ATYR
SCHEMBL4208352 0.85 TYR (0.58) HSD17B10MEN1MAPTKMT2ATTR
SCHEMBL11718847 0.83 ALOX5 (0.67) HSD17B10MEN1MAPTKMT2ACYP3A4
SCHEMBL696223 0.83 HSD17B10 (0.54) HSD17B10MEN1MAPTKMT2ATTR
SCHEMBL11329428 0.83 HSD17B10 (0.54) HSD17B10MEN1MAPTKMT2ATTR
SCHEMBL13817372 0.81 HSD17B10 (0.52) HSD17B10MEN1MAPTKMT2ATTR
SCHEMBL6165426 0.81 HSD17B10 (0.52) HSD17B10MEN1MAPTKMT2ATTR
SCHEMBL10942834 0.81 HSD17B10 (0.52) HSD17B10MEN1MAPTKMT2ATTR
SCHEMBL1607208 0.81 HSD17B10 (0.52) HSD17B10MEN1MAPTKMT2ATTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1138719-B1 POLYIMIDE/POLYARYLATE RESIN COMPOSITIONS AND MOLDINGS THEREOF TEIJIN LTD (JP) 2005-02-16 EP disclosed
US-6610794-B1 Excellent heat resistance, moldability, dimensional stability and transparency TEIJIN LIMITED (JP) 2003-08-26 US disclosed
EP-1138719-A1 POLYIMIDE/POLYARYLATE RESIN COMPOSITIONS AND MOLDINGS THEREOF TEIJIN LIMITED (JP) 2001-10-04 EP disclosed
EP-0333445-B1 Aromatic allene compounds and preparation thereof NIPPON PAINT CO LTD (JP) 1995-01-18 EP disclosed
US-5340931-A Chemical intermediates for allyl or vinyl ether polymers NIPPON PAINT CO., LTD. (JP) 1994-08-23 US disclosed
EP-0457334-B1 Carbonates of acetylenic alcohols NIPPON PAINT CO LTD (JP) 1994-08-10 EP disclosed
US-5258542-A Carbonates of acetylenic alcohols NIPPON PAINT CO., LTD. (JP) 1993-11-02 US disclosed
US-5194653-A Useful in making heat resistant liquid crystalline polymers NIPPON PAINT COMPANY, LIMITED (JP) 1993-03-16 US disclosed
EP-0457334-A1 Carbonates of acetylenic alcohols NIPPON PAINT CO., LTD. (JP) 1991-11-21 EP disclosed
EP-0333445-A2 Aromatic allene compounds and preparation thereof NIPPON PAINT CO., LTD. (JP) 1989-09-20 EP disclosed
US-4320144-A Fungicidal use of diphenyl esters of alkylenes GAF CORPORATION (US) 1982-03-16 US disclosed