Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16034529 | 1.00 | TSHR (0.50) | TSHRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL34839 | 1.00 | — | — | |
| Water SCHEMBL16716815 | 0.95 | — | — | |
| Potassium Ion SCHEMBL8720018 | 0.95 | TSHR (0.46) | TSHRKDM4EALDH1A1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28250941 | 0.95 | — | — | |
| Methane SCHEMBL28579750 | 0.95 | — | — | |
| Water SCHEMBL122257 | 0.95 | — | — | |
| SCHEMBL3361189 | 0.95 | — | — | |
| Fluoride SCHEMBL22288153 | 0.95 | — | — | |
| Formaldehyde SCHEMBL28274567 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208500-A1 | POLYMERS CONTAINING REPEATING UNITS WITH SEVERAL METAL OR ORGANIC SULPHONATE UNITS, METHODS FOR PREPARING SAME AND USES THEREOF | CDP-Innovation (FR) | 2023-07-12 | — | — | EP | claimed |
| WO-2022049236-A1 | POLYMERS CONTAINING REPEATING UNITS WITH SEVERAL METAL OR ORGANIC SULPHONATE UNITS, METHODS FOR PREPARING SAME AND USES THEREOF | CDP INNOVATION (FR) | 2022-03-10 | — | — | WO | claimed |
| CN-118223043-B | Porous manganese dioxide and preparation method and application thereof | 长沙学院 | 2024-10-18 | — | — | CN | disclosed |
| CN-118223043-A | Porous manganese dioxide and preparation method and application thereof | 长沙学院 | 2024-06-21 | — | — | CN | disclosed |
| EP-4208500-A1 | POLYMERS CONTAINING REPEATING UNITS WITH SEVERAL METAL OR ORGANIC SULPHONATE UNITS, METHODS FOR PREPARING SAME AND USES THEREOF | CDP-Innovation (FR) | 2023-07-12 | — | — | EP | disclosed |
| CN-114601800-A | Methylphosphopropofol sodium sterile powder injection and preparation method thereof | 瑞普（天津）生物药业有限公司 | 2022-06-10 | — | — | CN | disclosed |
| WO-2022049236-A1 | POLYMERS CONTAINING REPEATING UNITS WITH SEVERAL METAL OR ORGANIC SULPHONATE UNITS, METHODS FOR PREPARING SAME AND USES THEREOF | CDP INNOVATION (FR) | 2022-03-10 | — | — | WO | disclosed |
| CN-112424359-A | Compositions and methods for treating parkinson's disease | 沃雅戈治疗公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-112313331-A | Method for measuring efficacy of AADC viral vector | 沃雅戈治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-112042521-A | Transplanting method for test-tube plantlet of rhizome plant | 阳山县三连阳生态农林开发有限公司 | 2020-12-08 | — | — | CN | disclosed |
| EP-2969210-A1 | METHODS OF REMOVING CALCIUM MATERIAL FROM A SUBSTRATE OR CATALYTIC CONVERTER | STEAG Energy Services GmbH (DE) | 2016-01-20 | — | — | EP | disclosed |
| US-9061275-B2 | Methods of removing calcium material from a substrate or catalytic converter | STEAG ENERGY SERVICES GMBH (DE) | 2015-06-23 | — | — | US | disclosed |
| WO-2014158378-A1 | METHODS OF REMOVING CALCIUM MATERIAL FROM A SUBSTRATE OR CATALYTIC CONVERTER | STEAG ENERGY SERVICES GMBH (DE) | 2014-10-02 | — | — | WO | disclosed |
| US-20140274661-A1 | METHODS OF REMOVING CALCIUM MATERIAL FROM A SUBSTRATE OR CATALYTIC CONVERTER | STEAG ENERGY SERVICES GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| EP-1051655-A4 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1051655-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | Ista Pharmaceuticals, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999039238-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | KERATOFORM, INC. (US) | 1999-08-05 | — | — | WO | disclosed |
| EP-0078709-B1 | PREPARATION OF NITROARALKYL CYANIDES AND DERIVATIVES THEREOF | ETHYL CORPORATION (US) | 1986-10-01 | — | — | EP | disclosed |