Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 known ✓ | P25103 | 3/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6923620 | 0.90 | TACR1 (0.30) | TACR1CES2 | |
| Hydrochloric Acid SCHEMBL6923485 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL7650580 | 0.76 | — | — | |
| SCHEMBL6929363 | 0.75 | RXRA (0.36) | CES2 | |
| Hydrochloric Acid SCHEMBL6923166 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL6927034 | 0.66 | TACR1 (0.34) | TACR1 | |
| Hydrochloric Acid SCHEMBL3946480 | 0.64 | CNR1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL6285166 | 0.64 | S1PR1 (0.32) | — | |
| SCHEMBL6930680 | 0.64 | CNR1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL6927237 | 0.64 | TACR1 (0.34) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518378-B2 | Using an unbridged cyclopentadienyl metallocene catalyst capable of interconverting between states with different copolymerization characteristics | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2003-02-11 | — | — | US | disclosed |
| US-20010049425-A1 | High-melting polyolefin copolymer elastomers, catalysts and methods of synthesis | BP CORPORATION NORTH AMERICA INC. | 2001-12-06 | — | — | US | disclosed |
| US-20010034426-A1 | High-melting polyolefin copolymer elastomers, catalysts and methods of synthesis | BP CORPORATION NORTH AMERICA INC. | 2001-10-25 | — | — | US | disclosed |