SCHEMBL6928452

SCHEMBL6928452

O=C(O)COc1ccc([Te]c2ccc(OCC(=O)O)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.63
ALDH1A1 P00352 3/20 0.58
SMN1; SMN2 Q16637 1/20 0.56
FFAR1 O14842 1/20 0.56
PTPN7 P35236 2/20 0.55
MAPT P10636 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
PTPN12 Q05209 1/20 0.55
TSHR P16473 2/20 0.51
NR4A1 P22736 1/20 0.51
APEX1 P27695 1/20 0.51
PPARD Q03181 2/20 0.47
PPARG P37231 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MCL1 Q07820 1/20 0.47
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9544330 0.93 ALOX15 (0.55) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL9810678 0.88 ALOX15 (0.63) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL339492 0.87 ALOX15 (0.81) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL30969690 0.81 ALOX15 (0.65) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL18935767 0.81 ALOX15 (0.65) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL40485 0.81 ALOX15 (0.65) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL2780802 0.80 ALOX15 (0.71) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL11552274 0.80 ALOX15 (0.71) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL7119757 0.80 ALDH1A1 (0.42) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
Ethylene Glycol SCHEMBL27792523 0.80 ALOX15 (0.59) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0747704-B1 Immunoassay element containing a diaryl telluride compound to increase its stability ORTHO CLINICAL DIAGNOSTICS INC (US) 2003-12-10 EP disclosed
EP-0903583-B1 Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements ORTHO CLINICAL DIAGNOSTICS INC (US) 2003-11-12 EP disclosed
US-5928886-A SUPPORT HAVING ZONE OF ENZYME LABELED LIGAND OR ENZYME LABELED RECEPTOR, SPREADING ZONE, ZONE OF IMMOBILIZED RECEPTOR OF LIGAND, AND GRAVURE ZONE WITH DIARYL TELLURIDE; INCREASED STORAGE STABILITY JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1999-07-27 US disclosed
EP-0903583-A2 Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements Ortho-Clinical Diagnostics, Inc. (US) 1999-03-24 EP disclosed
US-5686254-A Reduction in first slide bias and improved enzyme stability by the incorporation of diaryl tellurides in thin-film immunoassay elements JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1997-11-11 US disclosed
EP-0747704-A2 Immunoassay element containing a diaryl telluride compound to increase its stability Johnson & Johnson Clinical Diagnostics, Inc. (US) 1996-12-11 EP disclosed