SCHEMBL9544330

SCHEMBL9544330

O=C(O)COc1ccc([Te]c2ccc(O)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.55
ALDH1A1 P00352 2/20 0.51
CYP19A1 P11511 1/20 0.51
ESR1 P03372 1/20 0.51
FFAR1 O14842 2/20 0.50
PPARD Q03181 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MEN1 O00255 1/20 0.49
MAPT P10636 1/20 0.49
PTPN7 P35236 1/20 0.49
KMT2A Q03164 1/20 0.49
PTPN12 Q05209 1/20 0.49
THRA P10827 1/20 0.48
THRB P10828 1/20 0.48
PPARG P37231 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6928452 0.93 ALOX15 (0.63) ALOX15ALDH1A1FFAR1PPARDSMN1; SMN2
SCHEMBL274850 0.89 ALOX15 (0.68) ALOX15ALDH1A1CYP19A1ESR1FFAR1
SCHEMBL4820127 0.83 ALOX15 (0.61) ALOX15ALDH1A1CYP19A1ESR1FFAR1
Formaldehyde SCHEMBL30592324 0.83 ALOX15 (0.61) ALOX15ALDH1A1CYP19A1ESR1FFAR1
Chloroacetic Acid SCHEMBL7821121 0.81 ALOX15 (0.59) ALOX15ALDH1A1CYP19A1ESR1FFAR1
SCHEMBL9543814 0.81 PTGS2 (0.54) ALDH1A1PPARDMEN1MAPTKMT2A
SCHEMBL9810678 0.81 ALOX15 (0.63) ALOX15ALDH1A1FFAR1PPARDSMN1; SMN2
SCHEMBL339492 0.80 ALOX15 (0.81) ALOX15ALDH1A1FFAR1PPARDSMN1; SMN2
SCHEMBL1550206 0.80 FFAR1 (0.77) ALOX15ALDH1A1CYP19A1ESR1FFAR1
SCHEMBL11261731 0.80 ESR1 (0.60) ALOX15ALDH1A1CYP19A1ESR1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993016993-A1 ANTIOXIDANT DIARYL TELLURIDES AKTIEBOLAGET ASTRA (SE) 1993-09-02 WO disclosed