SCHEMBL6928459

SCHEMBL6928459

Clc1cc(Cl)c2[c]c[nH]c2c1Cl

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
HPGD P15428 2/20 0.32
TSHR P16473 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CASP1 P29466 1/20 0.32
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9300156 0.65 ALDH1A1 (0.35) CYP3A4TSHRHSD17B10GRIN2DGRIN3B
SCHEMBL3833231 0.63 AHR (0.31)
SCHEMBL4885600 0.61 CSNK2A1 (0.32)
SCHEMBL9941338 0.61 ALDH1A1 (0.35) CYP3A4TSHRHSD17B10GRIN2DGRIN3B
SCHEMBL432617 0.58 CYP3A4 (0.38) CYP3A4HPGDTSHRHSD17B10CASP1
Pentachlorobenzene SCHEMBL183144 0.57 CYP3A4 (1.00) CYP3A4HPGDTSHRHSD17B10CASP1
Pentachlorobenzene SCHEMBL11455164 0.57 CYP3A4 (1.00) CYP3A4HPGDTSHRHSD17B10CASP1
SCHEMBL4478128 0.56 AHR (0.42) TSHR
SCHEMBL321694 0.56 GPR84 (0.41) TSHR
SCHEMBL2809723 0.55 HPGD (0.43) CYP3A4HPGDTSHRHSD17B10CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0897428-A4 TEST MEDIA AND QUANTITATIVE METHOD FOR IDENTIFICATION AND DIFFERENTIATION OF BIOLOGICAL MATERIALS IN A TEST SAMPLE RCR SCIENT INC (US) 2003-05-07 EP claimed
EP-0897428-A1 TEST MEDIA AND QUANTITATIVE METHOD FOR IDENTIFICATION AND DIFFERENTIATION OF BIOLOGICAL MATERIALS IN A TEST SAMPLE RCR Scientific, Inc. (US) 1999-02-24 EP claimed
WO-1997036001-A1 TEST MEDIA AND QUANTITATIVE METHOD FOR IDENTIFICATION AND DIFFERENTIATION OF BIOLOGICAL MATERIALS IN A TEST SAMPLE RCR SCIENTIFIC, INC. (US) 1997-10-02 WO claimed
US-5364767-A 6-chloroindole derivatives; colorimetric and quantitative analysis RESEARCH ORGANICS, IN. (US) 1994-11-15 US disclosed