Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | FABP2 | P12104 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17319669 | 0.85 | AKR1C3 (0.57) | PTGS2PTGS1AKR1C3AKR1C2CYP1A2 | |
| SCHEMBL27523133 | 0.79 | PTGS2 (0.45) | PTGS2PTGS1AKR1C3AKR1C2CYP1A2 | |
| SCHEMBL2393839 | 0.78 | PTGS2 (0.56) | PTGS2PTGS1AKR1C3AKR1C2MEN1 | |
| SCHEMBL2126514 | 0.77 | PTGS1 (0.44) | PTGS2PTGS1AKR1C3AKR1C2CYP1A2 | |
| SCHEMBL10938462 | 0.77 | IDO1 (0.55) | PTGS2PTGS1AKR1C3AKR1C2CYP1A2 | |
| SCHEMBL23366313 | 0.77 | PTGS2 (0.43) | PTGS2MEN1KMT2ATSHRMAPT | |
| SCHEMBL8479916 | 0.77 | PTGS2 (0.58) | PTGS2PTGS1AKR1C3AKR1C2MEN1 | |
| Biphenyl SCHEMBL7876282 | 0.77 | PTGS2 (0.58) | PTGS2PTGS1AKR1C3AKR1C2MEN1 | |
| SCHEMBL17319666 | 0.74 | KLK7 (0.49) | PTGS2PTGS1AKR1C3AKR1C2CYP1A2 | |
| SCHEMBL15641308 | 0.74 | AKR1B1 (0.53) | PTGS2PTGS1AKR1C3AKR1C2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1241913-C | Method of preparing 2-phenyl-3-naphthyl propionic acid derivative | DAIICHI SEIYAKU CO (JP) | 2006-02-15 | — | — | CN | disclosed |
| CN-1535954-A | Method of preparing 2-phenyl-3-naphthyl propionic acid derivative | 第一制药株式会社 | 2004-10-13 | — | — | CN | disclosed |
| CN-1535955-A | Method of preparing 2-phenyl-3-naphthyl propionic acid derivative | 第一制药株式会社 | 2004-10-13 | — | — | CN | disclosed |
| US-6515142-B2 | Intermediates of aromatic amidine derivatives which have anticoagulation action | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20020062033-A1 | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-05-23 | — | — | US | disclosed |
| US-6337405-B1 | MULTISTAGE REACTION OF PYRROLE SUBSTITUTED WITH SULFONATE GROUPS AND HYDROXYPHENYLACETIC ACID | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6252088-B1 | COUPLING A NITRILE CONTAININ NAPHTHALENE COMPOUND WITH A COMPOUND CONTAINING PROPIONIC ACID GROUP | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0936215-A1 | PROCESS FOR PREPARING 2-PHENYL-3-NAPHTHYLPROPIONIC ACID DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020062033-A1 | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | PROC, F12, F2 | PTGS2 2033/4885PTGS1 1892/4885AKR1C3 850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.