Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10644129 | 0.86 | SIGMAR1 (0.51) | KDM1AMEN1KMT2ASIGMAR1EBP | |
| SCHEMBL30192046 | 0.85 | SIGMAR1 (0.53) | KDM1AMEN1KMT2ASIGMAR1EBP | |
| SCHEMBL9583389 | 0.82 | KDM1A (0.53) | KDM1AMEN1KMT2ASIGMAR1EBP | |
| SCHEMBL390762 | 0.80 | ALDH1A1 (0.42) | KDM1AMEN1KMT2ASIGMAR1TP53 | |
| SCHEMBL17603661 | 0.78 | KDM1A (0.44) | KDM1AMEN1KMT2ASIGMAR1TP53 | |
| SCHEMBL4019674 | 0.77 | KDM1A (0.56) | KDM1AMEN1KMT2ASIGMAR1EBP | |
| SCHEMBL30460648 | 0.77 | KDM1A (0.56) | KDM1AMEN1KMT2ASIGMAR1EBP | |
| SCHEMBL6923877 | 0.76 | SIGMAR1 (0.49) | KDM1AMEN1KMT2ASIGMAR1EBP | |
| SCHEMBL9584099 | 0.76 | KDM1A (0.47) | KDM1AMEN1KMT2ASIGMAR1TP53 | |
| SCHEMBL30411876 | 0.75 | SIGMAR1 (0.51) | KDM1AMEN1KMT2ASIGMAR1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865276-A4 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | GILAD GAD (IL) | 2003-07-30 | — | — | EP | claimed |
| EP-0865276-A1 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | Gilad, Gad (IL) | 1998-09-23 | — | — | EP | claimed |
| WO-1997002027-A1 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1997-01-23 | — | — | WO | claimed |
| EP-0865276-A4 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | GILAD GAD (IL) | 2003-07-30 | — | — | EP | disclosed |
| EP-0865276-A1 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | Gilad, Gad (IL) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997002027-A1 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1997-01-23 | — | — | WO | disclosed |