Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.62 |
| ▸ | ECE1 | P42892 | 15/20 | 0.60 |
| ▸ | MME | P08473 | 14/20 | 0.60 |
| ▸ | CPA1 | P15085 | 1/20 | 0.58 |
| ▸ | CPB1 | P15086 | 1/20 | 0.58 |
| ▸ | CPA2 | P48052 | 1/20 | 0.58 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.58 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621126 | 0.89 | ECE1 (0.74) | ECE1MME | |
| SCHEMBL5916386 | 0.88 | ACE2 (0.56) | ACE2ECE1MMECPA1CPB1 | |
| SCHEMBL5034257 | 0.86 | ECE1 (0.50) | ACE2ECE1MME | |
| SCHEMBL5071371 | 0.85 | ECE1 (0.55) | ACE2ECE1MME | |
| SCHEMBL5034289 | 0.84 | ECE1 (0.53) | ACE2ECE1MME | |
| SCHEMBL6927137 | 0.84 | ECE1 (0.72) | ECE1MME | |
| SCHEMBL6928069 | 0.83 | ACE2 (0.81) | ACE2ECE1MME | |
| SCHEMBL5070497 | 0.82 | ECE1 (0.49) | ACE2ECE1MME | |
| SCHEMBL24991305 | 0.82 | ANPEP (0.54) | ACE2MMECPA1CPA2CPA4 | |
| SCHEMBL7611003 | 0.82 | ANPEP (0.54) | ACE2MMECPA1CPA2CPA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518260-B1 | (α-aminophosphino) peptide derivatives, method for making same and therapeutic applications thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2003-02-11 | — | — | US | disclosed |