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Sugi Predict / Compounds / SCHEMBL6927137

SCHEMBL6927137

SCHEMBL6927137

CC(C)(C)OC(=O)NC(Cc1ccccc1)P(=O)(O)CC(Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ECE1 P42892 19/20 0.72
▸ MME P08473 17/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7621126 0.90 ECE1 (0.74) ECE1MME
SCHEMBL6925939 0.90 ECE1 (0.88) ECE1MME
SCHEMBL6928169 0.89 ECE1 (0.57) ECE1MME
SCHEMBL7621700 0.84 ECE1 (1.00) ECE1MME
SCHEMBL3865859 0.84 ECE1 (0.66) ECE1MME
SCHEMBL6929264 0.84 ACE2 (0.62) ECE1MME
SCHEMBL27487988 0.81 CTSS (0.65) —
SCHEMBL3821800 0.81 CTSS (0.65) —
SCHEMBL27487987 0.81 CTSS (0.65) —
SCHEMBL3355326 0.81 CTSS (0.64) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518260-B1 (α-aminophosphino) peptide derivatives, method for making same and therapeutic applications thereof INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2003-02-11 — — US disclosed