Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194103 | 0.95 | TSHR (0.34) | TSHRTP53CYP3A4ALDH1A1 | |
| SCHEMBL10168261 | 0.83 | TSHR (0.41) | TSHRTP53CYP3A4ALDH1A1THRB | |
| SCHEMBL12804129 | 0.82 | TSHR (0.47) | TSHRTP53CYP3A4ALDH1A1THRB | |
| SCHEMBL6930405 | 0.81 | TSHR (0.37) | TSHRTP53CYP3A4ALDH1A1THRB | |
| SCHEMBL158386 | 0.81 | TSHR (0.57) | TSHRALDH1A1THRB | |
| SCHEMBL27534721 | 0.79 | TSHR (0.46) | TSHRCYP3A4ALDH1A1THRB | |
| SCHEMBL195286 | 0.77 | TSHR (0.42) | TSHRTP53CYP3A4ALDH1A1 | |
| SCHEMBL17123129 | 0.77 | LMNA (0.41) | TP53CYP3A4ALDH1A1 | |
| SCHEMBL6930399 | 0.77 | TSHR (0.33) | TSHRTP53CYP3A4 | |
| SCHEMBL29278361 | 0.76 | ALDH1A1 (0.44) | TSHRCYP3A4ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610802-B2 | Polymerizing unsatd. monomers with a transition metal catalyst and a coordination compound-forming ligand; filtration using a filter aid having carboxylic acid-, sulfonic acid- or phosphonic acid-containing units | ROHMAX ADDITIVES GMBH (DE) | 2003-08-26 | — | — | US | disclosed |
| US-20030060587-A1 | Process for synthesis of polymer compositions, polymer compositions obtainable by the process, and use of the same | ROHMAX ADDITIVES GMBH (DE) | 2003-03-27 | — | — | US | disclosed |