Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929891 | 0.80 | ALDH1A1 (0.60) | ADORA3IRAK4RAB9ANPC1SMN1; SMN2 | |
| Diethylamine SCHEMBL6929894 | 0.78 | IRAK4 (0.53) | ADORA3IRAK4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6932644 | 0.75 | KDM4E (0.58) | ADORA3IRAK4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6934460 | 0.74 | S1PR1 (0.41) | SMN1; SMN2MEN1KMT2AHPGDHTT | |
| SCHEMBL17582863 | 0.70 | MEN1 (0.46) | RAB9ANPC1LMNAMEN1KMT2A | |
| SCHEMBL17582867 | 0.70 | MEN1 (0.46) | RAB9ANPC1LMNAMEN1KMT2A | |
| SCHEMBL3604861 | 0.67 | IRAK4 (0.80) | ADORA3IRAK4RAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6930435 | 0.66 | RAB9A (0.62) | ADORA3IRAK4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11705152 | 0.66 | RAB9A (0.68) | IRAK4RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL4913650 | 0.66 | SCD (0.88) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660870-B1 | Serotonergic compounds which possess agonist activity at 5-HT2 receptors effectively lower and control normal and elevated IOP and are useful for treating glaucoma | ALCON, INC. (CH) | 2003-12-09 | — | — | US | disclosed |