Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.68 |
| ▸ | NPC1 | O15118 | 10/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705140 | 0.90 | RAB9A (0.68) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL11703485 | 0.89 | RAB9A (0.73) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL11207978 | 0.81 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL11700747 | 0.81 | NPC1 (0.69) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL11705598 | 0.80 | RAB9A (0.70) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL11706816 | 0.79 | NPC1 (1.00) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL12391455 | 0.79 | KDR (0.72) | SMN1; SMN2LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL11703469 | 0.79 | RAB9A (0.73) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL22193346 | 0.76 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL29610185 | 0.76 | ALDH1A1 (0.60) | RAB9ANPC1MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011236-A | N-(BENZIMIDAZOL-2-YL)ARYLCARBOXAMIDES AS ULTRAVIOLET (UV) LIGHT ABSORBERS | MERCK & CO., INC. (US) | 1977-03-08 | — | — | US | disclosed |