Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29767585 | 1.00 | HTR7 (0.39) | HTR7HTR1ANISCHPOLBBRD4 | |
| SCHEMBL29514531 | 0.83 | HTR7 (0.40) | HTR7HTR1ANISCHPOLBBRD4 | |
| SCHEMBL2971023 | 0.82 | HTR1A (0.33) | HTR7HTR1ANISCHPOLBKDM4E | |
| Indene SCHEMBL28986670 | 0.82 | CA1 (0.41) | HTR7HTR1ANISCHPOLBKDM4E | |
| SCHEMBL2966321 | 0.81 | KDM4E (0.36) | HTR7HTR1ANISCHKDM4EGAA | |
| SCHEMBL29616816 | 0.80 | HTR7 (0.36) | HTR7HTR1ANISCHPOLBBRD4 | |
| SCHEMBL6055951 | 0.79 | HTR7 (0.31) | HTR7HTR1ANISCHALDH1A1CYP1A2 | |
| SCHEMBL25428608 | 0.78 | HTR7 (0.37) | HTR7HTR1ANISCHPOLBKDM4E | |
| SCHEMBL2972002 | 0.78 | DHFR (0.33) | NISCHBRD4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29399101 | 0.77 | HSD17B10 (0.44) | KDM4EALDH1A1HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710491-B1 | (DI)SILICON BRIDGED METALLOCENES THAT PRODUCE POLYETHYLENE BROAD MOLECULAR WEIGHT DISTRIBUTION AND MOLECULAR WEIGHT | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2025-01-01 | — | — | EP | disclosed |
| CN-111372954-B | Preparation of polyethylene (bis) silicon-bridged metallocenes with broad molecular weight distribution and molecular weight | 埃克森美孚化学专利公司 | 2022-06-28 | — | — | CN | disclosed |
| US-11214631-B2 | (Di)silicon bridged metallocenes that produce polyethylene with broad molecular weight distribution and high molecular weight | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2022-01-04 | — | — | US | disclosed |
| EP-3710491-A1 | (DI)SILICON BRIDGED METALLOCENES THAT PRODUCE POLYETHYLENE BROAD MOLECULAR WEIGHT DISTRIBUTION AND MOLECULAR WEIGHT | ExxonMobil Chemical Patents Inc. (US) | 2020-09-23 | — | — | EP | disclosed |
| CN-111372954-A | Preparation of polyethylene (bis) silicon-bridged metallocenes with broad molecular weight distribution and molecular weight | 埃克森美孚化学专利公司 | 2020-07-03 | — | — | CN | disclosed |
| EP-3539993-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| US-20190144571-A1 | (Di)Silicon Bridged Metallocenes that Produce Polyethylene with Broad Molecular Weight Distribution and High Molecular Weight | EXXONMOBIL CHEMICAL PATENTS INC. | 2019-05-16 | — | — | US | disclosed |
| EP-3022233-B1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-05-01 | — | — | EP | disclosed |
| US-20180066083-A1 | Cyclopropyl Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-03-08 | — | — | US | disclosed |
| US-9834628-B2 | Cyclopropyl substituted metallocene catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-12-05 | — | — | US | disclosed |
| EP-3022233-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015009473-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-01-22 | — | — | WO | disclosed |
| US-20150025207-A1 | Cyclopropyl Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-01-22 | — | — | US | disclosed |
| EP-1027314-A4 | COUPLING REACTIONS OF 2-SUBSTITUTED, 7-HALOINDENES WITH ARYL SUBSTITUENTS TO PRODUCE METALLOCENE CATALYST LIGANDS | BOULDER SCIENT CO (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1027314-A1 | COUPLING REACTIONS OF 2-SUBSTITUTED, 7-HALOINDENES WITH ARYL SUBSTITUENTS TO PRODUCE METALLOCENE CATALYST LIGANDS | BOULDER SCIENTIFIC COMPANY (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-2000007968-A1 | COUPLING REACTIONS OF 2-SUBSTITUTED, 7-HALOINDENES WITH ARYL SUBSTITUENTS TO PRODUCE METALLOCENE CATALYST LIGANDS | BOULDER SCIENTIFIC COMPANY (US) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144571-A1 | (Di)Silicon Bridged Metallocenes that Produce Polyethylene with Broad Molecular Weight Distribution and High Molecular Weight | MDM4, MAL2, MSI2 | HTR7 2740/4885HTR1A 2408/4885NISCH 4675/4885 |
| US-20180066083-A1 | Cyclopropyl Substituted Metallocene Catalysts | CPNE4, TIMM13, NECTIN4 | HTR7 4100/4885HTR1A 1327/4885NISCH 2441/4885 |
| US-11214631-B2 | (Di)silicon bridged metallocenes that produce polyethylene with broad molecular weight distribution and high molecular weight | MDM4, MAL2, MSI2 | HTR7 2740/4885HTR1A 2408/4885NISCH 4675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.