Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301186 | 0.97 | ALDH1A1 (0.38) | CNR2KCNJ11ALDH1A1TSHRKIF11 | |
| SCHEMBL7796059 | 0.90 | KCNQ3 (0.34) | CNR2KCNJ11ALDH1A1TSHRKIF11 | |
| SCHEMBL2229892 | 0.86 | P2RX1 (0.40) | CNR2ALDH1A1TSHRKIF11MAPT | |
| SCHEMBL30391892 | 0.86 | P2RX1 (0.40) | CNR2ALDH1A1TSHRKIF11MAPT | |
| SCHEMBL1044125 | 0.84 | HSD17B2 (0.42) | ALDH1A1TSHRKIF11MAPTCYP2A6 | |
| SCHEMBL1305632 | 0.81 | CES1 (0.40) | ALDH1A1TSHRMAPTL3MBTL1CYP2A6 | |
| Iodide SCHEMBL7946567 | 0.81 | HSD17B2 (0.40) | ALDH1A1TSHRKIF11MAPTCYP2A6 | |
| Hydrochloric Acid SCHEMBL7937212 | 0.81 | HSD17B2 (0.40) | ALDH1A1TSHRKIF11MAPTCYP2A6 | |
| Fluoride Ion SCHEMBL7946277 | 0.81 | HSD17B2 (0.40) | ALDH1A1TSHRKIF11MAPTCYP2A6 | |
| Bromide SCHEMBL7937216 | 0.81 | HSD17B2 (0.40) | ALDH1A1TSHRKIF11MAPTCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771812-B1 | Method for producing an optically active diphosphine | TAKASAGO PERFUMERY CO LTD (JP) | 2003-12-10 | — | — | EP | disclosed |
| US-5693868-A | REACTING 2,2'-BIS(TRIFLUOROMETHANESULFONYLOXY)-1,1-BINAPHTHYL WITH A PHOSPHINE OXIDE IN THE PRESENCE OF A TRANSITION METAL-PHOSPHINE COMPLEX | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0771812-A1 | Method for producing an optically active diphosphine | Takasago International Corporation (JP) | 1997-05-07 | — | — | EP | disclosed |