SCHEMBL2229892

SCHEMBL2229892

FC(F)(F)c1cc(P(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccc3ccccc3c2-c2c(P(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)ccc3ccccc23)cc(C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX1 P51575 1/20 0.40
P2RX3 P56373 1/20 0.40
P2RX4 Q99571 1/20 0.40
P2RX7 Q99572 1/20 0.40
MAPT P10636 4/20 0.35
KDM4E B2RXH2 3/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NFKB1 P19838 2/20 0.34
NFKB2 Q00653 2/20 0.34
RELA Q04206 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
ALDH1A1 P00352 3/20 0.33
KIF11 P52732 3/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP1B1 Q16678 2/20 0.33
HPGD P15428 2/20 0.33
CYP2A6 P11509 1/20 0.33
TSHR P16473 1/20 0.33
CYP1A1 P04798 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30391892 1.00 P2RX1 (0.40) P2RX1P2RX3P2RX4P2RX7MAPT
SCHEMBL8611244 0.92 P2RX1 (0.41) P2RX1P2RX3P2RX4P2RX7MAPT
SCHEMBL5083753 0.90 P2RX1 (0.36) P2RX1P2RX3P2RX4P2RX7MAPT
SCHEMBL8615377 0.87 P2RX1 (0.39) P2RX1P2RX3P2RX4P2RX7MAPT
SCHEMBL6930336 0.86 CNR2 (0.38) P2RX1P2RX3P2RX4P2RX7MAPT
SCHEMBL30894430 0.84 MAPT (0.35) MAPTMEN1KMT2ATDP1ALDH1A1
SCHEMBL1304771 0.84 MAPT (0.35) MAPTMEN1KMT2ATDP1ALDH1A1
SCHEMBL301186 0.83 ALDH1A1 (0.38) MAPTTDP1ALDH1A1KIF11HSD17B10
SCHEMBL8613773 0.81 P2RX1 (0.39) P2RX1P2RX3P2RX4P2RX7MAPT
SCHEMBL7798355 0.80 CYP1A2 (0.37) MAPTKDM4EMEN1KMT2ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2981560-B1 CURING OF LIQUID THERMOSETTING RESINS REICHHOLD LLC 2 (US) 2021-10-13 EP claimed
US-9068045-B2 Curing of liquid thermosetting resins REICHHOLD, INC. (US) 2015-06-30 US claimed
US-20140303315-A1 CURING OF LIQUID THERMOSETTING RESINS Polynt Composites USA Inc. 2014-10-09 US claimed
EP-1598053-B1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres OREAL (FR) 2006-12-20 EP claimed
US-20050251928-A1 Method for stripping artificial color from keratin fibers L'OREAL (FR) 2005-11-17 US claimed
US-12071498-B2 Radically polymerizable compositions Polynt Composites USA, Inc. (US) 2024-08-27 US disclosed
US-20230257500-A1 RADICALLY POLYMERIZABLE COMPOSITIONS BNY MELLON CORPORATE TRUSTEE SERVICES LIMITED, AS SECURITY AGENT (GB) 2023-08-17 US disclosed
US-20230165771-A1 PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION L'OREAL (FR) 2023-06-01 US disclosed
CN-115996701-A Method for treating keratin fibres using a high concentration of a specific amino acid 莱雅公司 2023-04-21 CN disclosed
US-11518834-B2 Radically polymerizable compositions Polynt Composites USA, Inc. (US) 2022-12-06 US disclosed
EP-3906265-A1 RADICALLY POLYMERIZABLE COMPOSITIONS Polynt Composites USA Inc. (US) 2021-11-10 EP disclosed
EP-2981560-B1 CURING OF LIQUID THERMOSETTING RESINS REICHHOLD LLC 2 (US) 2021-10-13 EP disclosed
EP-2981560-A1 CURING OF LIQUID THERMOSETTING RESINS Reichhold, Inc. (US) 2016-02-10 EP disclosed
US-9068045-B2 Curing of liquid thermosetting resins REICHHOLD, INC. (US) 2015-06-30 US disclosed
US-20140303315-A1 CURING OF LIQUID THERMOSETTING RESINS Polynt Composites USA Inc. 2014-10-09 US disclosed
WO-2014165425-A1 CURING OF LIQUID THERMOSETTING RESINS REICHHOLD, INC. (US) 2014-10-09 WO disclosed
US-8445711-B2 Metal complexes LUCITE INTERNATIONAL UK LIMITED (GB) 2013-05-21 US disclosed
WO-2011089985-A1 COSMETIC COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2011-07-28 WO disclosed
US-20090312561-A1 METAL COMPLEXES LUCITE INTERNATIONAL UK LIMITED (GB) 2009-12-17 US disclosed
US-20050251928-A1 Method for stripping artificial color from keratin fibers L'OREAL (FR) 2005-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165771-A1 PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION KRT18, CKAP4, VIM P2RX1 4792/4885P2RX3 4811/4885P2RX4 4769/4885
US-20050251928-A1 Method for stripping artificial color from keratin fibers KRT18, DSG1, JUP P2RX1 4634/4885P2RX3 4489/4885P2RX4 3962/4885
US-20090312561-A1 METAL COMPLEXES MLX, PICALM, AP2M1 P2RX1 175/4885P2RX3 267/4885P2RX4 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.