Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932118 | 0.86 | ALDH1A1 (0.59) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10395364 | 0.84 | ALDH1A1 (0.45) | ALDH1A1LMNACYP3A4GAATSHR | |
| SCHEMBL6932279 | 0.79 | CYP2D6 (0.44) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL453729 | 0.78 | TRPA1 (0.50) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10079180 | 0.78 | ALDH1A1 (0.65) | ALDH1A1LMNACYP2D6CYP3A4MEN1 | |
| SCHEMBL7688086 | 0.77 | CYP1A2 (0.57) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6928569 | 0.77 | CYP1A2 (0.57) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL95127 | 0.77 | TRPA1 (0.48) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6933453 | 0.77 | TRPA1 (0.48) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10587361 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363587-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P&G-Clairol, Inc. (US) | 2003-11-26 | — | — | EP | disclosed |
| US-6409773-B1 | AMINOPHENOL COUPLERS | CLAIROL INCORPORATED | 2002-06-25 | — | — | US | disclosed |
| WO-2002047635-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P&G-CLAIROL, INC. (US) | 2002-06-20 | — | — | WO | disclosed |