Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTR1E | P28566 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936671 | 0.81 | CETP (0.62) | MAPK1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL14491597 | 0.76 | L3MBTL1 (0.60) | L3MBTL1HDAC4NPSR1LMNAGAA | |
| SCHEMBL175272 | 0.73 | MEN1 (0.71) | MAPK1L3MBTL1MEN1KMT2ANPSR1 | |
| SCHEMBL113558 | 0.73 | MEN1 (0.71) | MAPK1L3MBTL1MEN1KMT2ANPSR1 | |
| SCHEMBL27514539 | 0.73 | KMT2A (0.50) | MAPK1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL18400472 | 0.73 | LMNA (0.61) | L3MBTL1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL17502816 | 0.72 | HDAC4 (1.00) | L3MBTL1HDAC4MEN1KMT2ANPSR1 | |
| SCHEMBL16132896 | 0.72 | HDAC4 (1.00) | L3MBTL1HDAC4MEN1KMT2ANPSR1 | |
| SCHEMBL6857920 | 0.71 | KMT2A (0.73) | MAPK1L3MBTL1MEN1KMT2ANPSR1 | |
| SCHEMBL11332310 | 0.71 | KMT2A (0.73) | MAPK1L3MBTL1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000047-B1 | 1-(N-PHENYLAMINOALKYL)-PIPERAZINE DERIVATIVES SUBSTITUTED AT POSITION 2 OF THE PHENYL RING | RECORDATI CHEM PHARM (CH) | 2003-12-17 | — | — | EP | disclosed |
| CN-1127493-C | 1-(N-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of phenyl ring | RECORDATI CHEM PHARM (CH) | 2003-11-12 | — | — | CN | disclosed |
| CN-1265654-A | 1-(N-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of phenyl ring | RECORDATI CHEM PHARM (CH) | 2000-09-06 | — | — | CN | disclosed |
| US-6071920-A | BIND TO 5HT 1A RECEPTORS FOR TREATING DISORDERS OF THE LOWER URINARY TRACT; CNS DISORDERS; ANXIOLYTIC AGENTS; ANTIDEPRESSANTS; HYPOTENSIVE AGENTS; SLEEP AND EATING DISORDERS | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2000-06-06 | — | — | US | disclosed |
| EP-1000047-A1 | 1-(N-PHENYLAMINOALKYL)-PIPERAZINE DERIVATIVES SUBSTITUTED AT POSITION 2 OF THE PHENYL RING | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006384-A1 | 1-(N-PHENYLAMINOALKYL)-PIPERAZINE DERIVATIVES SUBSTITUTED AT POSITION 2 OF THE PHENYL RING | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1999-02-11 | — | — | WO | disclosed |