Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL2637741 | 0.94 | LMNA (0.53) | ALDH1A1LMNATP53MEN1TSHR | |
| Glycerin SCHEMBL28447412 | 0.86 | TP53 (0.52) | ALDH1A1LMNATP53THRB | |
| Glycerin SCHEMBL3358540 | 0.85 | TP53 (0.58) | ALDH1A1LMNATP53MEN1TSHR | |
| Glycerin SCHEMBL1712543 | 0.85 | TP53 (0.58) | ALDH1A1LMNATP53MEN1TSHR | |
| Glycerin SCHEMBL11173648 | 0.85 | TP53 (0.58) | ALDH1A1LMNATP53MEN1TSHR | |
| Glycerin SCHEMBL2856963 | 0.85 | TP53 (0.58) | ALDH1A1LMNATP53MEN1TSHR | |
| Glycerin SCHEMBL1712541 | 0.85 | TP53 (0.58) | ALDH1A1LMNATP53MEN1TSHR | |
| Glycerin SCHEMBL29119754 | 0.85 | TP53 (0.58) | ALDH1A1LMNATP53MEN1TSHR | |
| Glycerin SCHEMBL29119760 | 0.85 | TP53 (0.58) | ALDH1A1LMNATP53MEN1TSHR | |
| Glycerin SCHEMBL27263776 | 0.85 | TP53 (0.58) | ALDH1A1LMNATP53MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6641743-B1 | Methods for forming waveguides in optical materials | FEAC AGENT, LLC,, AS THE SUCCESSOR COLLATERAL AGENT | 2003-11-04 | — | — | US | disclosed |