Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.35 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557093 | 0.91 | CASP1 (0.49) | CASP1TSHRPDE10ACYP1A2CYP2D6 | |
| SCHEMBL95127 | 0.90 | TRPA1 (0.48) | CASP1TSHRCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3862347 | 0.84 | CASP1 (0.43) | CASP1TSHRPDE10ACYP1A2CYP2D6 | |
| SCHEMBL6933453 | 0.79 | TRPA1 (0.48) | CASP1TSHRCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29670126 | 0.78 | — | — | |
| SCHEMBL93860 | 0.78 | — | — | |
| SCHEMBL4869221 | 0.78 | CASP1 (1.00) | CASP1TSHRPDE10ACYP1A2CYP2D6 | |
| SCHEMBL11443273 | 0.78 | TDP1 (0.43) | CASP1TSHRCYP3A4MEN1KMT2A | |
| SCHEMBL453729 | 0.77 | TRPA1 (0.50) | CASP1TSHRCYP1A2CYP2D6CYP2C9 | |
| Dimethylamine SCHEMBL9021118 | 0.77 | CASP1 (0.86) | CASP1TSHRPDE10ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556816-B1 | Permanent hair dye in the form of foam | AROMA PLC (BG) | 2019-06-26 | — | — | EP | disclosed |
| EP-2422762-A1 | Stable oxidative colouring composition for keratin fibers | KPSS-Kao Professional Salon Services GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |