SCHEMBL693140

SCHEMBL693140

Cc1ccc(N)cc1O.Cc1ccc(NCCO)cc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 2/20 0.59
TSHR P16473 1/20 0.59
ALDH1A1 P00352 4/20 0.47
TUBB4A P04350 1/20 0.42
TUBB P07437 1/20 0.42
TUBA3C P0DPH7 1/20 0.42
TUBA1B P68363 1/20 0.42
TUBA4A P68366 1/20 0.42
TUBB4B P68371 1/20 0.42
TUBB3 Q13509 1/20 0.42
TUBB2A Q13885 1/20 0.42
TUBB8 Q3ZCM7 1/20 0.42
TUBA3E Q6PEY2 1/20 0.42
TUBA1A Q71U36 1/20 0.42
TUBA1C Q9BQE3 1/20 0.42
TUBB6 Q9BUF5 1/20 0.42
TUBB2B Q9BVA1 1/20 0.42
TUBB1 Q9H4B7 1/20 0.42
PDE10A Q9Y233 1/20 0.42
CYP1A2 P05177 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6557096 0.91 CASP1 (0.47) CASP1TSHRALDH1A1TUBB4ATUBB
SCHEMBL29428385 0.90 ALDH1A1 (0.56) CASP1TSHRALDH1A1TUBB4ATUBB
SCHEMBL95129 0.90 ALDH1A1 (0.56) CASP1TSHRALDH1A1TUBB4ATUBB
Sulfuric Acid SCHEMBL17976587 0.83 ALDH1A1 (0.53) CASP1ALDH1A1TUBB4ATUBBTUBA3C
SCHEMBL5822705 0.82 TUBB1 (0.47) CASP1TSHRALDH1A1TUBB4ATUBB
SCHEMBL3862352 0.82 CASP1 (0.39) CASP1TSHRALDH1A1TUBB4ATUBB
SCHEMBL6390338 0.81 ALDH1A1 (0.42) CASP1TSHRALDH1A1TUBB4ATUBB
SCHEMBL4888143 0.80 ALDH1A1 (0.41) CASP1TSHRALDH1A1TUBB4ATUBB
SCHEMBL30202433 0.80 ALDH1A1 (0.67) CASP1TSHRALDH1A1TUBB4ATUBB
SCHEMBL456096 0.80 ALDH1A1 (0.67) CASP1TSHRALDH1A1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106102696-A Composition of detergent 宝洁公司 2016-11-09 CN disclosed
EP-2422762-A1 Stable oxidative colouring composition for keratin fibers KPSS-Kao Professional Salon Services GmbH (DE) 2012-02-29 EP disclosed