Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934494 | 0.86 | KMT2A (0.46) | TSHRKMT2A | |
| SCHEMBL6937304 | 0.75 | EGFR (0.34) | ALDH1A1KMT2AHTT | |
| SCHEMBL6068857 | 0.73 | SMN1; SMN2 (0.39) | TSHRL3MBTL1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6068854 | 0.73 | SMN1; SMN2 (0.39) | TSHRL3MBTL1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL28340761 | 0.72 | CA12 (0.44) | SMN1; SMN2ALDH1A1KMT2ANFE2L2HPGD | |
| SCHEMBL5026209 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1KMT2ANFE2L2HTR1A | |
| SCHEMBL6932141 | 0.70 | TRPA1 (0.41) | TSHRL3MBTL1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9109781 | 0.70 | SMN1; SMN2 (0.46) | TSHRL3MBTL1SMN1; SMN2ALDH1A1NFE2L2 | |
| SCHEMBL8425831 | 0.69 | CYP1A2 (0.47) | TSHRSMN1; SMN2ALDH1A1NFE2L2HTR1A | |
| SCHEMBL7068243 | 0.69 | KMT2A (0.41) | TSHRSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370547-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002081464-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2002-10-17 | — | — | WO | disclosed |