Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24443105 | 0.79 | P4HB (0.41) | TRPA1P4HBTSHRGABRA1GABRB2 | |
| SCHEMBL6934494 | 0.77 | KMT2A (0.46) | TSHRPOLBCA12CA2LMNA | |
| SCHEMBL11855485 | 0.76 | P4HB (0.39) | P4HBTSHRGABRA1GABRB2ALDH1A1 | |
| SCHEMBL24743672 | 0.76 | P4HB (0.39) | P4HBTSHRGABRA1GABRB2ALOX15 | |
| SCHEMBL79176 | 0.76 | GABRA1 (0.44) | P4HBTSHRGABRA1GABRB2ALOX15 | |
| SCHEMBL9198990 | 0.76 | GABRA1 (0.44) | P4HBTSHRGABRA1GABRB2MAOA | |
| SCHEMBL6937304 | 0.73 | EGFR (0.34) | TRPA1ALDH1A1EGFRLMNA | |
| SCHEMBL9198984 | 0.72 | GABRA1 (0.41) | P4HBTSHRGABRA1GABRB2ALOX15 | |
| SCHEMBL6931481 | 0.70 | TSHR (0.40) | TSHRALDH1A1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL11289083 | 0.68 | GABRA1 (0.38) | P4HBTSHRGABRA1GABRB2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370547-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002081464-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2002-10-17 | — | — | WO | disclosed |