Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934494 | 0.84 | KMT2A (0.46) | KMT2ALMNAAGTR1CYP1A2 | |
| SCHEMBL6931481 | 0.75 | TSHR (0.40) | KMT2AALDH1A1HTT | |
| SCHEMBL6069132 | 0.73 | CYP1A2 (0.36) | EGFRLMNAAGTR1CYP1A2PTPN1 | |
| SCHEMBL6069136 | 0.73 | CYP1A2 (0.36) | EGFRLMNAAGTR1CYP1A2PTPN1 | |
| SCHEMBL6932141 | 0.73 | TRPA1 (0.41) | EGFRLMNATRPA1ALDH1A1 | |
| SCHEMBL30741239 | 0.69 | CA12 (0.48) | EGFRLMNAAGTR1CYP1A2PTPN1 | |
| SCHEMBL30741241 | 0.69 | CA12 (0.48) | EGFRLMNAAGTR1CYP1A2PTPN1 | |
| SCHEMBL3185351 | 0.69 | CA12 (0.48) | EGFRLMNAAGTR1CYP1A2PTPN1 | |
| SCHEMBL7068243 | 0.68 | KMT2A (0.41) | KMT2ALMNAAGTR1CYP1A2ALDH1A1 | |
| SCHEMBL9900083 | 0.68 | TP53 (0.36) | EGFRLMNAPTPN1TRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370547-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002081464-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2002-10-17 | — | — | WO | disclosed |