Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.41 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.39 |
| ▸ | SARS1 | P49591 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | IARS1 | P41252 | 1/20 | 0.38 |
| ▸ | MARS1 | P56192 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.35 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26882824 | 0.88 | STING1 (0.45) | ADORA3RXFP1RAPGEF3ALDH1A1LMNA | |
| SCHEMBL6936922 | 0.86 | ADORA3 (0.51) | ADORA3LARS1SARS1DNMT1IARS1 | |
| SCHEMBL26780958 | 0.85 | STING1 (0.47) | STING1 | |
| SCHEMBL14946312 | 0.85 | STING1 (0.47) | STING1 | |
| SCHEMBL1798803 | 0.82 | PDE4A (0.45) | RXFP1ACHEALDH1A1LMNATP53 | |
| SCHEMBL1798801 | 0.82 | PDE4A (0.45) | RXFP1ACHEALDH1A1LMNATP53 | |
| SCHEMBL5963251 | 0.81 | STING1 (0.38) | ADORA3NT5ESTING1 | |
| SCHEMBL8939099 | 0.81 | STING1 (0.38) | ADORA3NT5ESTING1 | |
| SCHEMBL8939101 | 0.81 | STING1 (0.38) | ADORA3NT5ESTING1 | |
| SCHEMBL6362480 | 0.79 | ADORA2A (0.37) | ADORA3SARS1STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967220-B1 | Novel arabinosyladenine derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6242429-B1 | ANTIVIRAL ARA-A DERIVATIVES HAVING RESISTANCE TO METABOLISM BY ADENOSINEDEAMINASE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0967220-A1 | Novel arabinosyladenine derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1999-12-29 | — | — | EP | disclosed |