Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 6/20 | 0.38 |
| ▸ | HINT1 | P49773 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939101 | 1.00 | STING1 (0.38) | STING1HINT1ADORA2AADORA2BHSP90B1 | |
| SCHEMBL5963251 | 1.00 | STING1 (0.38) | STING1HINT1ADORA2AADORA2BHSP90B1 | |
| SCHEMBL5963100 | 0.88 | STING1 (0.47) | STING1HINT1ADORA2AADORA2BHSP90B1 | |
| SCHEMBL7197488 | 0.86 | ADORA2A (0.37) | STING1ADORA2AADORA2BADORA3 | |
| SCHEMBL6362480 | 0.86 | ADORA2A (0.37) | STING1ADORA2AADORA2BADORA3 | |
| SCHEMBL1582124 | 0.83 | HINT1 (0.39) | STING1HINT1ADORA2AADORA2BHSP90B1 | |
| SCHEMBL4759035 | 0.83 | ADORA3 (0.41) | STING1ADORA2AADORA2BNT5EADORA3 | |
| SCHEMBL1797958 | 0.81 | PDE4A (0.44) | STING1ADORA3 | |
| SCHEMBL29792984 | 0.81 | PDE4A (0.44) | STING1ADORA3 | |
| SCHEMBL6931629 | 0.81 | ADORA3 (0.41) | STING1NT5EADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506351-A | Process for the preparation of 2'-O-alkyl guanosine and related compounds | ISIS PHARMACEUTICALS (US) | 1996-04-09 | — | — | US | disclosed |