Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.51 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.42 |
| ▸ | SARS1 | P49591 | 1/20 | 0.42 |
| ▸ | IARS1 | P41252 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963100 | 0.91 | STING1 (0.47) | ADORA3RAPGEF3RXFP1STING1LMNA | |
| SCHEMBL8594450 | 0.90 | AHCY (0.50) | ADORA3DNMT1STING1LMNANT5E | |
| SCHEMBL22216550 | 0.90 | ADORA3 (0.54) | ADORA3RXFP1DNMT1LMNANT5E | |
| SCHEMBL4757808 | 0.90 | ADORA3 (0.54) | ADORA3RXFP1DNMT1LMNANT5E | |
| SCHEMBL19961896 | 0.90 | ADORA3 (0.54) | ADORA3RXFP1DNMT1LMNANT5E | |
| SCHEMBL22983991 | 0.86 | STING1 (0.56) | ADORA3RAPGEF3RXFP1STING1LMNA | |
| SCHEMBL6895355 | 0.86 | STING1 (0.56) | ADORA3RAPGEF3RXFP1STING1LMNA | |
| SCHEMBL16271105 | 0.86 | STING1 (0.56) | ADORA3RAPGEF3RXFP1STING1LMNA | |
| SCHEMBL23813544 | 0.86 | STING1 (0.56) | ADORA3RAPGEF3RXFP1STING1LMNA | |
| SCHEMBL9964279 | 0.86 | STING1 (0.56) | ADORA3RAPGEF3RXFP1STING1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967220-B1 | Novel arabinosyladenine derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6242429-B1 | ANTIVIRAL ARA-A DERIVATIVES HAVING RESISTANCE TO METABOLISM BY ADENOSINEDEAMINASE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0967220-A1 | Novel arabinosyladenine derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1999-12-29 | — | — | EP | disclosed |