Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3676215 | 0.90 | CA1 (0.39) | ALDH1A1CYP1A2LMNAKDM4EAGTR1 | |
| E968 SCHEMBL17075261 | 0.90 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL252296 | 0.87 | ALDH1A1 (0.43) | ALDH1A1LMNATSHR | |
| Hydroquinone SCHEMBL4865328 | 0.84 | ALDH1A1 (0.38) | ALDH1A1CYP1A2LMNAMEN1CYP2C19 | |
| Phenol SCHEMBL9818392 | 0.82 | TDP1 (0.41) | ALDH1A1CYP1A2LMNAKDM4ECYP2C19 | |
| Glycerin SCHEMBL27533691 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CYP1A2LMNAKDM4EAGTR1 | |
| SCHEMBL28124160 | 0.80 | ALDH1A1 (0.38) | ALDH1A1CYP1A2LMNAKDM4EAGTR1 | |
| SCHEMBL8745121 | 0.80 | TSHR (0.39) | ALDH1A1CYP1A2LMNAKDM4EMEN1 | |
| SCHEMBL7768640 | 0.78 | ALDH1A1 (0.33) | ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL7768631 | 0.77 | GBA1 (0.33) | ALDH1A1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216142-A4 | THERMOFORMABLE OPHTHALMIC LENS | NOVARTIS AG (CH) | 2003-06-11 | — | — | EP | disclosed |
| EP-1216142-A1 | THERMOFORMABLE OPHTHALMIC LENS | Wesley Jessen Corporation (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001005578-A1 | THERMOFORMABLE OPHTHALMIC LENS | WESLEY-JESSEN CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |