E968

E968

SCHEMBL17075261

C=Cc1ccccc1COCc1ccccc1C=C.OC[C@@H](O)[C@@H](O)CO

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
IDO1 P14902 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL6931928 0.90 ALDH1A1 (0.34) ALDH1A1
SCHEMBL252296 0.87 ALDH1A1 (0.43) ALDH1A1IDO1
E968 SCHEMBL17075256 0.85 TACR1 (0.31)
Hydroquinone SCHEMBL4865328 0.84 ALDH1A1 (0.38) ALDH1A1IDO1
SCHEMBL3676215 0.83 CA1 (0.39) ALDH1A1
Phenol SCHEMBL9818392 0.82 TDP1 (0.41) ALDH1A1IDO1
SCHEMBL30917971 0.82 ALDH1A1 (0.36) ALDH1A1
SCHEMBL8745121 0.80 TSHR (0.39) ALDH1A1
SCHEMBL7768640 0.78 ALDH1A1 (0.33) ALDH1A1
SCHEMBL7768631 0.77 GBA1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10966909-B2 Resin composites for use in dental preventive and restorative applications ADA FOUNDATION (US) 2021-04-06 US disclosed
US-20200297587-A1 RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS ADA FOUNDATION (US) 2020-09-24 US disclosed
US-10675224-B2 Enzymatically and hydrolytically stable dental preventive and restorative systems ADA FOUNDATION (US) 2020-06-09 US disclosed
US-20190209438-A1 ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS ADA FOUNDATION (US) 2019-07-11 US disclosed
US-10231906-B2 Enzymatically and hydrolytically stable dental preventive and restorative systems ADA FOUNDATION (US) 2019-03-19 US disclosed
EP-3270870-A1 ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS ADA FOUNDATION (US) 2018-01-24 EP disclosed
US-20170049666-A1 ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS ADA FOUND (US) 2017-02-23 US disclosed
US-9572753-B2 Enzymatically and hydrolytically stable resins, resin monomers, and resin composites for use in dental preventive and restorative applications ADA FOUNDATION (US) 2017-02-21 US disclosed
WO-2016160299-A1 ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS ADA FOUNDATION (US) 2016-10-06 WO disclosed
US-20150257986-A1 ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS ADA FOUNDATION 2015-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190209438-A1 ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS GGH, DNPH1, BCHE ALDH1A1 321/4885IDO1 2109/4885
US-10675224-B2 Enzymatically and hydrolytically stable dental preventive and restorative systems GGH, DNPH1, BCHE ALDH1A1 321/4885IDO1 2109/4885
US-10966909-B2 Resin composites for use in dental preventive and restorative applications SUV39H2, CBX3, SUV39H1 ALDH1A1 1332/4885IDO1 4443/4885
US-20170049666-A1 ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS GGH, DNPH1, BCHE ALDH1A1 321/4885IDO1 2109/4885
US-20200297587-A1 RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS SUV39H2, CBX3, SUV39H1 ALDH1A1 1332/4885IDO1 4443/4885
US-20150257986-A1 ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS ESD, JMJD6, DNPH1 ALDH1A1 377/4885IDO1 3296/4885
US-10231906-B2 Enzymatically and hydrolytically stable dental preventive and restorative systems GGH, DNPH1, BCHE ALDH1A1 321/4885IDO1 2109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.