Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252296 | 0.84 | ALDH1A1 (0.43) | TSHRTACR1ALDH1A1LMNAMAPK1 | |
| SCHEMBL20855968 | 0.83 | CYSLTR1 (0.44) | LTA4HMAPTLMNATP53CYSLTR1 | |
| Hydroquinone SCHEMBL4865328 | 0.81 | ALDH1A1 (0.38) | TSHRLTA4HCA1CA2CA9 | |
| Glycerin SCHEMBL6931928 | 0.80 | ALDH1A1 (0.34) | TSHRKDM4ECA1CA2CA7 | |
| E968 SCHEMBL17075261 | 0.80 | ALDH1A1 (0.34) | ALDH1A1 | |
| Phenol SCHEMBL9818392 | 0.80 | TDP1 (0.41) | TSHRLTA4HKDM4ECA1POLB | |
| SCHEMBL8344663 | 0.77 | MAPT (0.51) | TSHRKDM4EALDH1A1L3MBTL1NPC1 | |
| SCHEMBL7768640 | 0.75 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8344768 | 0.75 | PTGER4 (0.35) | TSHRKDM4EL3MBTL1NPC1MAPT | |
| SCHEMBL11234470 | 0.75 | TSHR (0.65) | TSHRTACR1KDM4ECA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466220-B1 | Carboxy containing monomers and polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5278267-A | Water insoluble vinyl aromatic polymer | EASTMAN KODAK COMPANY (US) | 1994-01-11 | — | — | US | disclosed |
| US-5210289-A | Homo or coploymers for medical diagnosis | EASTMAN KODAK COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| US-5149737-A | Carboxy group extended from polymer surface allows easier attachment of biological substances | EASTMAN KODAK COMPANY (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0466220-A2 | Carboxy containing monomers and polymers and latices prepared from same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |