Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389515 | 0.74 | JAK2 (0.46) | ALDH1A1ADORA2BADORA3ADORA2AADORA1 | |
| SCHEMBL4381730 | 0.74 | ADORA2B (0.34) | ALDH1A1ADORA2BADORA3KMT2AADORA2A | |
| SCHEMBL29048925 | 0.72 | ADORA2B (0.35) | ALDH1A1KDM4EADORA2BHPGDADORA3 | |
| SCHEMBL23923454 | 0.71 | TYMP (0.35) | KDM4EHPGDHSD17B10GAA | |
| SCHEMBL6888253 | 0.68 | JAK2 (0.52) | — | |
| SCHEMBL11160084 | 0.67 | MAPT (0.53) | ALDH1A1ADORA2BHPGDADORA3HSD17B10 | |
| SCHEMBL1144956 | 0.67 | ALDH1A1 (0.36) | ALDH1A1KDM4EADORA2BHPGDADORA3 | |
| SCHEMBL3443608 | 0.67 | HSD17B10 (0.45) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL14833537 | 0.64 | L3MBTL1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL22032779 | 0.63 | TP53 (0.38) | ALDH1A1KDM4EHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092038-A4 | OCT1p, A PROTEIN HAVING HOMOLOGY TO THE ORGANIC AND SUGAR TRANSPORTER FAMILY OF PROTEINS, AND USES THEREOF | MILLENNIUM PHARM INC (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-1092038-A1 | OCT1p, A PROTEIN HAVING HOMOLOGY TO THE ORGANIC AND SUGAR TRANSPORTER FAMILY OF PROTEINS, AND USES THEREOF | Millennium Pharmaceuticals, Inc. (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000633-A1 | OCT1p, A PROTEIN HAVING HOMOLOGY TO THE ORGANIC AND SUGAR TRANSPORTER FAMILY OF PROTEINS, AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2000-01-06 | — | — | WO | disclosed |