SCHEMBL6932491

SCHEMBL6932491

CCc1ccc(COO)c(CC)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.42
AKT1 P31749 1/20 0.39
BACE1 P56817 1/20 0.38
POLB P06746 1/20 0.38
GPR84 Q9NQS5 1/20 0.37
SOD1 P00441 1/20 0.37
ALDH1A1 P00352 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
DHFR P00374 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8750429 0.83 TRPA1 (0.40) TRPA1AKT1BACE1POLBGPR84
SCHEMBL8750671 0.82 TDP1 (0.42) TRPA1AKT1BACE1POLBGPR84
SCHEMBL444673 0.80 TRPA1 (0.48) TRPA1AKT1BACE1POLBALDH1A1
SCHEMBL606251 0.77 TRPA1 (0.46) TRPA1AKT1BACE1POLBALDH1A1
SCHEMBL5050079 0.76 TRPA1 (0.44) TRPA1AKT1BACE1ALDH1A1CYP1A2
Ethylene SCHEMBL27875997 0.76 TRPA1 (0.44) TRPA1AKT1BACE1POLBALDH1A1
Formic Acid SCHEMBL28752897 0.75 TRPA1 (0.45) TRPA1AKT1BACE1POLBGPR84
SCHEMBL8384809 0.74 TRPA1 (0.43) TRPA1AKT1BACE1POLBALDH1A1
SCHEMBL1411710 0.74 GABRA1 (0.46) ALDH1A1MAPTL3MBTL1
SCHEMBL11786079 0.73 LPL (0.46) TRPA1POLBALDH1A1CYP2A6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1366006-A1 PROCESS FOR PREPARING PHENOLS INEOS Phenol GmbH & Co. KG (DE) 2003-12-03 EP disclosed
WO-2002070442-A1 PROCESS FOR PREPARING PHENOLS INEOS PHENOL GMBH & CO. KG (DE) 2002-09-12 WO disclosed