Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL6932742

C=CC(=O)OC.CN(C)C

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.48
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
TSHR P16473 9/20 0.39
ALDH1A1 P00352 10/20 0.38
HPGD P15428 1/20 0.38
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 2/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.33
TGM2 P21980 1/20 0.32
FGFR4 P22455 1/20 0.32
THRB P10828 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL27465044 0.97 HCAR2 (0.46) HCAR2KEAP1NFE2L2TSHRALDH1A1
Acrylic Acid Methyl Ester SCHEMBL7643475 0.97 HCAR2 (0.46) HCAR2KEAP1NFE2L2TSHRALDH1A1
Acrylic Acid Methyl Ester SCHEMBL27696952 0.95 HCAR2 (0.43) HCAR2KEAP1NFE2L2TSHRALDH1A1
Acrylic Acid Methyl Ester SCHEMBL28476990 0.95 HCAR2 (0.43) HCAR2KEAP1NFE2L2TSHRALDH1A1
Acrylic Acid Methyl Ester SCHEMBL27524008 0.95 HCAR2 (0.43) HCAR2KEAP1NFE2L2TSHRALDH1A1
Acrylic Acid Methyl Ester SCHEMBL7645157 0.91 HCAR2 (0.56) HCAR2KEAP1NFE2L2TSHRALDH1A1
Acrylic Acid Methyl Ester SCHEMBL1854813 0.91 HCAR2 (0.56) HCAR2KEAP1NFE2L2TSHRALDH1A1
Acrylic Acid Methyl Ester SCHEMBL9108 0.91
Acrylic Acid Methyl Ester SCHEMBL29119971 0.91 HCAR2 (0.40) HCAR2KEAP1NFE2L2TSHRALDH1A1
Acrylic Acid Methyl Ester SCHEMBL28768538 0.89 TSHR (0.48) HCAR2KEAP1NFE2L2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102844401-A Expandable elastomeric material in presence of water or oil RHODIA OPERATIONS 2012-12-26 CN claimed
US-11185513-B1 Transfersome-containing transdermal film formulations and methods of use KING ABDULAZIZ UNIVERSITY (SA) 2021-11-30 US disclosed
CN-108478798-A A kind of preparation method for the micro- hydrogel that can load and be sustained simultaneously hydrophobe drug 浙江大学 2018-09-04 CN disclosed
WO-2018153977-A1 STABLE COMPOSITION OF TENOFOVIR ALAFENAMIDE HEXAL AG (DE) 2018-08-30 WO disclosed
CN-108350238-A Absorbent and protective compositions comprising elastomeric copolymers and superabsorbent materials 金伯利-克拉克环球有限公司 2018-07-31 CN disclosed
CN-107750172-A Hydrogel foam sheets for oxygen delivery and methods of manufacture 金伯利-克拉克环球有限公司 2018-03-02 CN disclosed
CN-107613932-A Deliver the absorbent article and manufacture method of oxygen 金伯利-克拉克环球有限公司 2018-01-19 CN disclosed
US-20160199282-A1 PERFORMANCE-ENHANCED HAIR TREATMENT COMPOSITION HENKEL AG & CO. KGAA (DE) 2016-07-14 US disclosed
CN-105636575-A Performance-enhanced hair treatment composition HENKEL AG & CO KGAA 2016-06-01 CN disclosed
CN-103270218-B Creped tissue products with enhanced retention KIMBERLY-CLARK WORLDWIDE, INC. (US) 2015-11-25 CN disclosed
CN-1668344-A Fluid storage material comprising particles immobilized with a cross-linkable adhesive composition KIMBERLY CLARK CO (US) 2005-09-14 CN disclosed
CN-1665549-A Absorbent binder desiccant composition and articles incorporating it KIMBERLY CLARK CO (US) 2005-09-07 CN disclosed
CN-1589304-A Water-absorbing agent, method for producing same, and absorbent article using same SAN DIA POLYMERS LTD (JP) 2005-03-02 CN disclosed
CN-1161435-C Hydrophilic adhesive material ������ҩ��ʽ���� 2004-08-11 CN disclosed
EP-0995610-B1 Ink jet recording element with overcoat layer EASTMAN KODAK CO (US) 2003-12-03 EP disclosed
US-6165499-A Transdermal therapeutic system with small application-area thickness and great flexibility, and production process LTS LOHMANN THERAPIE-SYSTEME GMBH (DE) 2000-12-26 US disclosed
US-6089704-A Overcoat for ink jet recording element EASTMAN KODAK COMPANY (US) 2000-07-18 US disclosed
EP-0995610-A2 Ink jet recording element with overcoat layer EASTMAN KODAK COMPANY (US) 2000-04-26 EP disclosed
CN-1243851-A Hydrophilic adhesive material SS PHARMACEUTICAL CO (JP) 2000-02-09 CN disclosed
CN-1219126-A Transdermal therampeutic system with small application-area thickness and great flexibility,and production process LOHMANN THERAPIE SYST LTS (DE) 1999-06-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160199282-A1 PERFORMANCE-ENHANCED HAIR TREATMENT COMPOSITION KRT18, YWHAZ, PHYKPL HCAR2 2935/4885KEAP1 2505/4885NFE2L2 3309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.