Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oleamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.74 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | CNR1 | P21554 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL28032209 | 1.00 | FAAH (0.74) | FAAHSOAT1MEN1KMT2ATP53 | |
| Oleamide SCHEMBL69329 | 1.00 | FAAH (0.74) | FAAHSOAT1MEN1KMT2ATP53 | |
| Diethanolamine SCHEMBL5808096 | 0.95 | KDM4E (0.77) | FAAHSOAT1MEN1KMT2ATP53 | |
| Diethanolamine SCHEMBL28070607 | 0.90 | SOAT1 (0.55) | FAAHSOAT1MEN1KMT2ATP53 | |
| Diethanolamine SCHEMBL6763687 | 0.90 | SOAT1 (0.55) | FAAHSOAT1MEN1KMT2ATP53 | |
| Octadecanoic Acid Amide SCHEMBL368172 | 0.90 | SOAT1 (0.55) | FAAHSOAT1MEN1KMT2ATP53 | |
| Oleamide SCHEMBL988693 | 0.89 | FAAH (0.77) | FAAHSOAT1MEN1KMT2ATP53 | |
| Propanol SCHEMBL9069871 | 0.88 | FAAH (0.89) | FAAHSOAT1MEN1KMT2ATP53 | |
| Oleamide SCHEMBL28238325 | 0.88 | FAAH (0.89) | FAAHSOAT1MEN1KMT2ATP53 | |
| Oleamide SCHEMBL2864007 | 0.88 | FAAH (0.89) | FAAHSOAT1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109984956-B | Natural silicone replacement for silicone fluids in personal care formulations | 伊诺莱克斯投资公司 | 2022-09-20 | — | — | CN | claimed |
| WO-2022128441-A1 | CLEANSING COMPOSITION | UNILEVER IP HOLDINGS B.V. (NL) | 2022-06-23 | — | — | WO | claimed |
| CN-112055728-A | Particulate stabilizer composition for polymer resins and process for producing the same | 塞特工业公司 | 2020-12-08 | — | — | CN | claimed |
| US-10292929-B2 | Natural silicone replacements for silicone fluids in personal care formulations | CITIZENS BANK, N.A. | 2019-05-21 | — | — | US | claimed |
| WO-2018134776-A1 | PRESERVATIVE FREE SHAMPOO COMPOSITIONS | DR. REDDY’S LABORATORIES LIMITED (IN) | 2018-07-26 | — | — | WO | claimed |
| US-9914867-B2 | Completion fluid friction reducer | NOLES INTELLECTUAL PROPERTIES, LLC (US) | 2018-03-13 | — | — | US | claimed |
| EP-3233204-A2 | COMPOSITION FOR ENHANCING HAIR FIBER PROPERTIES | The Procter & Gamble Company (US) | 2017-10-25 | — | — | EP | claimed |
| US-20170233627-A1 | Completion Fluid Friction Reducer | NOLES INTELLECTUAL PROPERTIES, LLC (US) | 2017-08-17 | — | — | US | claimed |
| US-20170196796-A1 | Natural Silicone Replacements for Silicone Fluids In Personal Care Formulations | CITIZENS BANK, N.A. | 2017-07-13 | — | — | US | claimed |
| US-20160175209-A1 | COMPOSITION FOR ENHANCING HAIR FIBER PROPERTIES | THE PROCTER & GAMBLE COMPANY | 2016-06-23 | — | — | US | claimed |
| US-7879790-B2 | Renewable surfactant, low foaming and low temperature performance for high efficiency washers and dishwashers, environmentally friendly as nontoxic, biodegradable, vegetable oil-derived, personal care and cleaning applications | STEPAN COMPANY (US) | 2011-02-01 | — | — | US | claimed |
| WO-2011010997-A1 | MIXED SALTS OF SULFONATED ESTOLIDES AND OTHER DERIVATIVES OF FATTY ACIDS, AND METHODS OF MAKING THEM | STEPAN COMPANY (US) | 2011-01-27 | — | — | WO | claimed |
| US-20100022429-A1 | Mixed Salts of Sulfonated Estolides and Other Derivatives of Fatty Acids, and Methods of Making Them | STEPAN COMPANY | 2010-01-28 | — | — | US | claimed |
| CN-1165287-C | Compositions contg. antifungal and cationic agent | ղɭҩҵ����˾ | 2004-09-08 | — | — | CN | claimed |
| US-20020095859-A1 | Micro-emulsion fuel additive | H2OIL CORPORATION | 2002-07-25 | — | — | US | claimed |
| CN-1242701-A | Compositions contg. antifungal and cationic agent | JANSSEN PHARMACEUTICA NV (BE) | 2000-01-26 | — | — | CN | claimed |
| US-5456851-A | Antidandruff agent; storage stability; improved lathering and conditioning | JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. (US) | 1995-10-10 | — | — | US | claimed |
| EP-0506744-A4 | AQUEOUS CLEANER/DEGREASER EMULSION COMPOSITIONS | — | 1993-09-22 | — | — | EP | claimed |
| EP-0506744-A1 | AQUEOUS CLEANER/DEGREASER EMULSION COMPOSITIONS | BUCKEYE INTERNATIONAL, INC. (US) | 1992-10-07 | — | — | EP | claimed |
| WO-1991009104-A1 | AQUEOUS CLEANER/DEGREASER EMULSION COMPOSITIONS | BUCKEYE INTERNATIONAL, INC. (US) | 1991-06-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175209-A1 | COMPOSITION FOR ENHANCING HAIR FIBER PROPERTIES | PHOSPHO1, SGMS1, SGMS2 | FAAH 114/4885SOAT1 125/4885MEN1 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.