Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934617 | 0.82 | SLC6A4 (0.49) | ADRB1MEN1KMT2AHTTCHRM3 | |
| SCHEMBL6932177 | 0.80 | SIGMAR1 (0.52) | POLBADRB1MEN1KMT2AALDH1A1 | |
| SCHEMBL6931860 | 0.79 | BRS3 (0.48) | MEN1KMT2AALDH1A1RECQLCHRM3 | |
| SCHEMBL27918650 | 0.75 | SIGMAR1 (0.46) | POLBMEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL29313543 | 0.74 | CHRM3 (0.56) | POLBMEN1KMT2AALDH1A1CHRM3 | |
| SCHEMBL14238826 | 0.74 | POLB (0.88) | POLBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL29756483 | 0.74 | SIGMAR1 (0.62) | POLBADRB1MEN1KMT2AHRH3 | |
| SCHEMBL593734 | 0.74 | SIGMAR1 (0.62) | POLBADRB1MEN1KMT2AHRH3 | |
| SCHEMBL6931864 | 0.74 | HTT (0.54) | MEN1KMT2AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL2923966 | 0.73 | SIGMAR1 (0.61) | POLBADRB1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366030-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS | Neurogen Corporation (US) | 2003-12-03 | — | — | EP | claimed |
| WO-2002004433-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2002-01-17 | — | — | WO | claimed |