Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918650 | 0.93 | SIGMAR1 (0.46) | SIGMAR1L3MBTL1SLC6A4SLC6A2POLB | |
| SCHEMBL92506 | 0.81 | L3MBTL1 (0.63) | SIGMAR1L3MBTL1POLBHSD11B1ALDH1A1 | |
| SCHEMBL6934617 | 0.80 | SLC6A4 (0.49) | SIGMAR1SLC6A4SLC6A2KMT2AHTR3E | |
| SCHEMBL6933017 | 0.80 | POLB (0.56) | POLBKMT2AADRB1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL14110120 | 0.80 | SIGMAR1 (0.49) | SIGMAR1L3MBTL1POLBKMT2AHSD11B1 | |
| Hydrochloric Acid SCHEMBL14110124 | 0.80 | SIGMAR1 (0.49) | SIGMAR1L3MBTL1POLBKMT2AHSD11B1 | |
| SCHEMBL11083860 | 0.80 | FAAH (0.54) | SIGMAR1L3MBTL1SLC6A4SLC6A2POLB | |
| SCHEMBL9090627 | 0.80 | L3MBTL1 (0.61) | SIGMAR1L3MBTL1POLBHSD11B1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL20337874 | 0.80 | L3MBTL1 (0.61) | SIGMAR1L3MBTL1POLBKMT2AHSD11B1 | |
| SCHEMBL2431448 | 0.80 | SIGMAR1 (0.50) | SIGMAR1L3MBTL1SLC6A4SLC6A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366030-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS | Neurogen Corporation (US) | 2003-12-03 | — | — | EP | claimed |
| WO-2002004433-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2002-01-17 | — | — | WO | claimed |