Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.54 |
| ▸ | MAOA | P21397 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911046 | 0.85 | MAOB (0.57) | MAOBMAOAMAPTHTTL3MBTL1 | |
| SCHEMBL629952 | 0.84 | MAOB (0.74) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL13298042 | 0.84 | MAOB (0.77) | MAOBMAOAMRGPRX4 | |
| SCHEMBL15615390 | 0.81 | MAOB (0.58) | MAOBMAOAMAPTCA12CA1 | |
| SCHEMBL8303432 | 0.81 | CA12 (0.59) | MAPTCA12CA1CA2CA7 | |
| Methyl 2,4-Dihydroxybenzoate SCHEMBL5199862 | 0.81 | MAOB (0.68) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL7908741 | 0.80 | MAOB (0.56) | MAOBMAOAMAPTCA12CA1 | |
| SCHEMBL15615441 | 0.79 | MAOB (0.62) | MAOBMAOAMAPTHTTL3MBTL1 | |
| SCHEMBL4212043 | 0.79 | MAOB (0.58) | MAOBMAOAMAPTHTTCA12 | |
| SCHEMBL22438674 | 0.78 | CA12 (0.60) | MAOBMAOAMAPTL3MBTL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | disclosed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |