Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4212043 | 0.86 | MAOB (0.58) | MAOBMAOAMAPTHTTAPP | |
| SCHEMBL629952 | 0.86 | MAOB (0.74) | MAOBMAOAAPP | |
| SCHEMBL7910785 | 0.86 | MAOB (0.59) | MAOBMRGPRX4 | |
| SCHEMBL13298042 | 0.86 | MAOB (0.77) | MAOBMRGPRX4MAOA | |
| SCHEMBL6933053 | 0.85 | MAOB (0.54) | MAOBMRGPRX4MAOAMAPTHTT | |
| SCHEMBL294143 | 0.83 | CA12 (0.72) | MAPTHTTAPP | |
| Methyl 2,4-Dihydroxybenzoate SCHEMBL5199862 | 0.83 | MAOB (0.68) | MAOBMAOAAPP | |
| SCHEMBL3646136 | 0.82 | RAB9A (0.65) | MAOBMRGPRX4MAPTSPHK2SPHK1 | |
| SCHEMBL7908741 | 0.82 | MAOB (0.56) | MAOBMRGPRX4MAOAMAPT | |
| SCHEMBL27879847 | 0.82 | MRGPRX4 (0.64) | MAOBMRGPRX4MAOASPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |