Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856484 | 0.81 | ESR1 (0.45) | TAAR1TSHRHIF1ANR1H2ALOX15 | |
| SCHEMBL20449068 | 0.78 | MAOA (0.47) | TAAR1KDM4ESLC6A2 | |
| SCHEMBL10338884 | 0.75 | NR1H2 (0.50) | TAAR1TSHRNFKB1HIF1ANR1H2 | |
| SCHEMBL3724500 | 0.75 | NR1H2 (0.50) | TAAR1TSHRNFKB1HIF1ANR1H2 | |
| SCHEMBL11556171 | 0.75 | ESR1 (0.40) | TSHRHIF1ANR1H2KDM4EALOX15 | |
| SCHEMBL416542 | 0.72 | ALDH1A1 (0.41) | TSHRNR1H2ESR1ESR2CA2 | |
| SCHEMBL4960257 | 0.70 | ESR1 (0.46) | TAAR1TSHRNFKB1HIF1ANR1H2 | |
| SCHEMBL19788328 | 0.70 | NR1H2 (0.44) | TAAR1NFKB1HIF1ANR1H2KDM4E | |
| SCHEMBL10633915 | 0.70 | ESR1 (0.52) | TAAR1NFKB1HIF1ANR1H2KDM4E | |
| SCHEMBL1727364 | 0.70 | NR1H2 (0.44) | TAAR1NFKB1HIF1ANR1H2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199560-A1 | Bisaryl compound and medicament for cancer treatment comprising the same | KYOWA HAKKO KOGYO CO., LTD. | 2003-10-23 | — | — | US | disclosed |
| US-6608061-B2 | Antiproliferative agents | KYOMA HAKKO KOGYO CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| US-20030018070-A1 | BISARYL COMPOUND AND MEDICAMENT FOR CANCER TREATMENT COMPRISING THE SAME | FUJIFILM CORPORATION (JP) | 2003-01-23 | — | — | US | disclosed |
| EP-0990439-A1 | BISARYL COMPOUNDS AND CANCER REMEDIES CONTAINING THE SAME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018070-A1 | BISARYL COMPOUND AND MEDICAMENT FOR CANCER TREATMENT COMPRISING THE SAME | AR, NR5A1, SRD5A1 | TAAR1 935/4885HTR3A 942/4885TSHR 749/4885 |
| US-20030199560-A1 | Bisaryl compound and medicament for cancer treatment comprising the same | AR, NR5A1, SRD5A1 | TAAR1 935/4885HTR3A 942/4885TSHR 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.