Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | GAA | P10253 | 9/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 11/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | CASP6 | P55212 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14541439 | 0.92 | ALDH1A1 (0.57) | ALDH1A1GAATDP1HTTALOX15 | |
| SCHEMBL11331023 | 0.83 | NPSR1 (0.47) | ALDH1A1GAATDP1HTTMAPT | |
| SCHEMBL6572186 | 0.81 | PLA2G7 (0.50) | ALDH1A1GAATDP1HTTALOX15 | |
| SCHEMBL11206431 | 0.81 | GAA (0.65) | ALDH1A1GAATDP1HTTALOX15 | |
| SCHEMBL30514623 | 0.81 | GAA (0.65) | ALDH1A1GAATDP1HTTALOX15 | |
| SCHEMBL15966366 | 0.81 | TSHR (0.51) | ALDH1A1GAATDP1ALOX15MAPT | |
| SCHEMBL10397632 | 0.81 | GAA (0.44) | ALDH1A1GAATDP1HTTALOX15 | |
| SCHEMBL3455261 | 0.79 | HPGD (0.43) | ALDH1A1GAATDP1ALOX15MAPT | |
| SCHEMBL18383213 | 0.79 | TSHR (0.50) | ALDH1A1GAATDP1ALOX15MAPT | |
| SCHEMBL27887780 | 0.78 | ALDH1A1 (0.61) | ALDH1A1GAATDP1HTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186595-B1 | Diaryl-p-phenylenediamine disulfides | GOODYEAR TIRE & RUBBER (US) | 2003-11-26 | — | — | EP | disclosed |
| US-6627686-B1 | Mixture with rubber; oxidation resistance; tires, rolls, conveyor belts, footwear | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-09-30 | — | — | US | disclosed |
| EP-1186595-A1 | Diaryl-p-phenylenediamine disulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-03-13 | — | — | EP | disclosed |
| EP-0700963-B1 | Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines | GOODYEAR TIRE & RUBBER (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5726248-A | ANTIOXIDANTS FOR DIENE POLYMERS WITH HIGH MOLECULAR WEIGHTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0700963-A1 | Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-03-13 | — | — | EP | disclosed |