SCHEMBL6933409

SCHEMBL6933409

Cc1ccc(O)c(N)c1S(N)(=O)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.39
CA2 P00918 5/20 0.39
CA12 O43570 4/20 0.39
CA9 Q16790 4/20 0.39
TSHR P16473 1/20 0.39
CASP1 P29466 1/20 0.39
PDE10A Q9Y233 1/20 0.39
GAA P10253 3/20 0.39
HSD17B10 Q99714 3/20 0.39
GFER P55789 1/20 0.39
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 1/20 0.38
CA7 P43166 2/20 0.36
GLO1 Q04760 2/20 0.36
CA4 P22748 1/20 0.36
CA3 P07451 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10867140 0.81 ALDH1A1 (0.40) CA1CA2CA12CA9TSHR
SCHEMBL1804080 0.78 TRPA1 (0.39) CA1CA2CA12CA9TSHR
SCHEMBL10588952 0.75 CA2 (0.37) CA1CA2CA12CA9CASP1
SCHEMBL2929807 0.73 CA2 (0.41) CA1CA2CA12CA9GAA
SCHEMBL3296375 0.72 TRPA1 (0.48) CA1CA2CA12CA9GAA
SCHEMBL29469942 0.72 TRPA1 (0.48) CA1CA2CA12CA9GAA
SCHEMBL1522319 0.72 CA2 (0.40) CA1CA2CA12CA9TSHR
SCHEMBL31634585 0.72 PDE10A (0.54) TSHRCASP1PDE10AGAAHSD17B10
SCHEMBL4968725 0.72 PDE10A (0.54) TSHRCASP1PDE10AGAAHSD17B10
SCHEMBL10515286 0.72 CA12 (0.45) CA1CA2CA12CA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0777703-B1 DICYCLIC METAL COMPLEX FORMAZAN DERIVATIVES, PROCESS FOR PRODUCING THE SAME, COMPOSITION CONTAINING THE SAME AND DYEING PROCESS EMPLOYING THE SAME KYUNGIN SYNTHETIC CORP (KR) 2003-06-25 EP disclosed
US-5858026-A EXCELLENT DYEING PROPERTIES COMPARED TO THE TRICYCLIC METAL FORMAZAN COMPOUNDS; POST-DYEING SUNLIGHT AND WASHFASTNESS KYUNG-IN SYNTHETIC CORPORATION (KR) 1999-01-12 US disclosed