SCHEMBL6933468

SCHEMBL6933468

c1ccc(Cc2cnc3ccccc3c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 1/20 0.53
PDGFRA P16234 1/20 0.53
CYP1A2 P05177 1/20 0.50
PDE10A Q9Y233 7/20 0.49
KDM1A O60341 1/20 0.49
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
CFTR P13569 1/20 0.49
MGAM O43451 1/20 0.49
RAB9A P51151 2/20 0.46
CALM1 P0DP23 1/20 0.46
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
PKM P14618 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30644247 0.86 CYP1A2 (0.58) PDGFRBPDGFRACYP1A2PDE10ARAB9A
SCHEMBL1772519 0.86 BIRC5 (0.47) PDGFRBPDGFRACYP1A2PDE10AKDM1A
SCHEMBL28532450 0.85 PDGFRB (0.53) PDGFRBPDGFRACYP1A2KDM1AMAOA
SCHEMBL28050901 0.82 CYP11B1 (0.46) PDGFRBPDGFRACYP1A2PDE10A
SCHEMBL27522816 0.82 CYP1A2 (0.47) PDGFRBPDGFRACYP1A2PDE10AKDM1A
SCHEMBL3396692 0.82 CYP1A2 (0.55) PDGFRBPDGFRACYP1A2PDE10AKDM1A
Ethylbenzene SCHEMBL28002148 0.81 CYP1A2 (0.52) PDGFRBPDGFRACYP1A2PDE10AKDM1A
SCHEMBL6614214 0.81 PDGFRB (0.50) PDGFRBPDGFRACYP1A2PDE10AKDM1A
SCHEMBL22926854 0.81 PDE10A (0.49) CYP1A2PDE10ARAB9ACALM1KDM4E
SCHEMBL12277481 0.81 HTT (0.41) PDE10ACALM1KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0957891-B1 REDUCTION OF HAIR GROWTH GILLETTE CO (US) 2003-03-19 EP claimed
US-6037326-A APPLYING TO THE SKIN AN INHIBITOR OF A DNA TOPOISOMERASE GILLETTE COMPANY, THE 2000-03-14 US claimed
EP-0957891-A1 REDUCTION OF HAIR GROWTH HANDELMAN, Joseph H. (US) 1999-11-24 EP claimed
WO-1998029086-A1 REDUCTION OF HAIR GROWTH HANDELMAN, JOSEPH, H. (US) 1998-07-09 WO claimed
US-20250367649-A1 PHOTOCATALYSTS, PREPARATION AND USE THEREOF THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) 2025-12-04 US disclosed
CN-120040301-A Aromatic amine organic compound, mixture, composition and organic electronic device 广州华睿光电材料有限公司 2025-05-27 CN disclosed
CN-116354981-B Organic compound, mixture, composition and organic electronic device comprising same 广州华睿光电材料有限公司 2025-04-29 CN disclosed
CN-116082266-B Organic compounds, mixtures, compositions, light extraction layer materials and organic electronic devices 广州华睿光电材料有限公司 2025-02-28 CN disclosed
CN-119504816-A Organic compound containing boron-10 isotope and application thereof 广州工程技术职业学院 2025-02-25 CN disclosed
CN-115894254-B Organic compounds, mixtures, compositions and organic electronic devices 广州华睿光电材料有限公司 2025-02-14 CN disclosed
CN-119343338-A Aromatic amine organic compound and application thereof in organic electronic device 浙江光昊光电科技有限公司 2025-01-21 CN disclosed
CN-116178323-B Aromatic amine organic compound, mixture, composition and organic electronic device 广州华睿光电材料有限公司 2024-11-29 CN disclosed
US-20080227775-A1 Quinoline Derivatives as Antibacterial Agents JANSSEN PHARMACEUTICA N.V. (BE) 2008-09-18 US disclosed
US-7338949-B2 Mycobacterial inhibitors JANSSEN PHARMACEUTICA N.V. (BE) 2008-03-04 US disclosed
US-20070093478-A1 Novel mycobacterial inhibitors JANSSEN PHARMACEUTICA N.V. (BE) 2007-04-26 US disclosed
US-20070082895-A1 Novel mycobacterial inhibitors JANSSEN PHARMACEUTICA N.V. (BE) 2007-04-12 US disclosed
EP-0957891-B1 REDUCTION OF HAIR GROWTH GILLETTE CO (US) 2003-03-19 EP disclosed
US-6037326-A APPLYING TO THE SKIN AN INHIBITOR OF A DNA TOPOISOMERASE GILLETTE COMPANY, THE 2000-03-14 US disclosed
EP-0957891-A1 REDUCTION OF HAIR GROWTH HANDELMAN, Joseph H. (US) 1999-11-24 EP disclosed
WO-1998029086-A1 REDUCTION OF HAIR GROWTH HANDELMAN, JOSEPH, H. (US) 1998-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080227775-A1 Quinoline Derivatives as Antibacterial Agents NQO2, HRH1, HRH2 PDGFRB 2400/4885PDGFRA 2270/4885CYP1A2 182/4885
US-20070082895-A1 Novel mycobacterial inhibitors HRH4, NAT1, CBR3 PDGFRB 1930/4885PDGFRA 2385/4885CYP1A2 478/4885
US-20250367649-A1 PHOTOCATALYSTS, PREPARATION AND USE THEREOF PPOX, AOX1, CYP3A7 PDGFRB 3230/4885PDGFRA 2798/4885CYP1A2 11/4885
US-20070093478-A1 Novel mycobacterial inhibitors NQO2, NAT1, HRH1 PDGFRB 3090/4885PDGFRA 3504/4885CYP1A2 309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.