Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934809 | 0.86 | ELANE (0.37) | SMN1; SMN2RAB9AL3MBTL1ELANEOPRL1 | |
| SCHEMBL6931339 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2NPC1RAB9AELANEALDH1A1 | |
| SCHEMBL6933471 | 0.79 | ALDH1A1 (0.33) | SMN1; SMN2NPC1RAB9AL3MBTL1MMP2 | |
| SCHEMBL6935099 | 0.75 | PDE4A (0.36) | SMN1; SMN2NPC1RAB9AL3MBTL1MMP2 | |
| SCHEMBL6935359 | 0.75 | MAOB (0.37) | SMN1; SMN2NPC1RAB9AL3MBTL1MMP2 | |
| SCHEMBL6930285 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL6933583 | 0.72 | CFTR (0.45) | SMN1; SMN2NPC1RAB9AL3MBTL1MMP2 | |
| SCHEMBL6934453 | 0.72 | MAPT (0.43) | SMN1; SMN2NPC1RAB9AELANEALDH1A1 | |
| SCHEMBL6931093 | 0.72 | MAPT (0.43) | SMN1; SMN2NPC1RAB9AELANEALDH1A1 | |
| SCHEMBL6930598 | 0.72 | HPGD (0.41) | SMN1; SMN2NPC1RAB9AL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | claimed |
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |