Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | PPARD | Q03181 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | FAAH | O00519 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28006135 | 0.89 | CES2 (0.44) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| SCHEMBL9019586 | 0.89 | CES2 (0.44) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| SCHEMBL4645612 | 0.89 | CES2 (0.44) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| SCHEMBL23213954 | 0.89 | CES2 (0.44) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| SCHEMBL845324 | 0.89 | CES2 (0.44) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| SCHEMBL23213958 | 0.89 | CES2 (0.44) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| SCHEMBL9019580 | 0.89 | CES2 (0.44) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| SCHEMBL4645615 | 0.89 | CES2 (0.44) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| SCHEMBL845323 | 0.89 | CES2 (0.44) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| SCHEMBL12799601 | 0.86 | TERT (0.53) | TERTPTPN1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101842090-A | Topical composition for treating pain | XVASIVE INC | 2010-09-22 | — | — | CN | disclosed |
| EP-0852140-B1 | METHODS FOR MAKING HARDLY SOLUBLE MEDICINE AMORPHOUS | NISSAN CHEMICAL IND LTD (JP) | 2003-12-03 | — | — | EP | disclosed |
| EP-1356807-A2 | Method for converting sparingly water-soluble medical substance to amorphous state | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2003-10-29 | — | — | EP | disclosed |
| US-6462093-B1 | Method for converting sparingly water-soluble medical substance to amorphous state | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0852140-A1 | METHODS FOR MAKING HARDLY SOLUBLE MEDICINE AMORPHOUS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1998-07-08 | — | — | EP | disclosed |