Known targets — ChEMBL curated mechanism
SLC6A2SLC6A3SSTR1SSTR2SSTR3SSTR5
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL518280 | 0.94 | CA4 (0.48) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL161238 | 0.94 | CA4 (0.48) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL20400343 | 0.94 | CA4 (0.48) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL11903448 | 0.94 | CA4 (0.48) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL7635443 | 0.94 | CA4 (0.48) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL120390 | 0.94 | CA4 (0.52) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL1655126 | 0.94 | CA4 (0.48) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL21054602 | 0.94 | CA4 (0.52) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL22401093 | 0.94 | CA4 (0.52) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL16431397 | 0.94 | CA4 (0.48) | CA4CTSLCPT2CPT1ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115463124-B | Iron supplementing effervescent tablet and preparation method thereof | 海而思（郑州）科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-115463124-A | Iron-supplementing effervescent tablet and preparation method thereof | 海而思（郑州）科技有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-113317428-A | Calcium, iron and zinc solid preparation and preparation method thereof | 海而思（郑州）科技有限公司 | 2021-08-31 | — | — | CN | claimed |
| WO-2021137780-A1 | PREPARATION OF FILM TABLET COMPOSITION COMPRISING HEME IRON FOR IRON DEFICIENCY | İLKO İLAÇ SANAYİ VE TİCARET A.Ş. (TR) | 2021-07-08 | — | — | WO | claimed |
| EP-3216782-B1 | IRON AMINO ACID COMPOUNDS, METHOD FOR PREPARING IRON AMINO ACID COMPOUNDS, COMPOSITIONS CONTAINING IRON AMINO ACID COMPOUNDS, AND USES THEREOF | NPA NUCLEO DE PESQUISAS APLICADAS LTDA (BR) | 2021-06-02 | — | — | EP | claimed |
| US-20210122705-A1 | IRON AMINO ACID COMPOUNDS, METHOD FOR PREPARING IRON AMINO ACID COMPOUNDS, COMPOSITIONS CONTAINING IRON AMINO ACID COMPOUNDS, AND USES THEREOF | NPA NUCLEO DE PESQUISAS APLICADAS LTDA (BR) | 2021-04-29 | — | — | US | claimed |
| US-20180370903-A1 | IRON AMINO ACID COMPOUNDS, METHOD FOR PREPARING IRON AMINO ACID COMPOUNDS, COMPOSITIONS CONTAINING IRON AMINO ACID COMPOUNDS, AND USES THEREOF | NPA - NÚCLEO DE PESQUISAS APLICADAS LTDA. (BR) | 2018-12-27 | — | — | US | claimed |
| US-9913806-B2 | Patches and methods for the transdermal delivery of a therapeutically effective amount of iron | FE3 MEDICAL, INC. (US) | 2018-03-13 | — | — | US | claimed |
| EP-3216782-A1 | IRON AMINO ACID COMPOUNDS, METHOD FOR PREPARING IRON AMINO ACID COMPOUNDS, COMPOSITIONS CONTAINING IRON AMINO ACID COMPOUNDS, AND USES THEREOF | NPA - Núcleo De Pesquisas Aplicadas LTDA. (BR) | 2017-09-13 | — | — | EP | claimed |
| US-9731982-B2 | Surface modified ceramic filter | UNIVERSITY OF KANSAS (US) | 2017-08-15 | — | — | US | claimed |
| EP-2421601-A2 | METHOD FOR TRANSDERMAL IONTOPHORETIC DELIVERY OF CHELATED AGENTS | Incube Labs, Llc (US) | 2012-02-29 | — | — | EP | claimed |
| WO-2010123584-A2 | METHOD FOR TRANSDERMAL IONTOPHORETIC DELIVERY OF CHELATED AGENTS | INCUBE LABS, LLC (US) | 2010-10-28 | — | — | WO | claimed |
| US-20090035385-A1 | COMPOSITIONS INCLUDING IRON | DRUGTECH CORPORATION (US) | 2009-02-05 | — | — | US | claimed |
| EP-1827418-A2 | COMPOSITIONS INCLUDING IRON | Drugtech Corporation (US) | 2007-09-05 | — | — | EP | claimed |
| EP-1827419-A2 | METHODS AND COMPOSITIONS FOR ENHANCING IRON ABSORPTION | Drugtech Corporation (US) | 2007-09-05 | — | — | EP | claimed |
| WO-2006068697-A2 | COMPOSITIONS INCLUDING IRON | DRUGTECH CORPORATION (US) | 2006-06-29 | — | — | WO | claimed |
| WO-2006068729-A2 | METHODS AND COMPOSITIONS FOR ENHANCING IRON ABSORPTION | DRUGTECH CORPORATION (US) | 2006-06-29 | — | — | WO | claimed |
| US-20060134227-A1 | Compositions including iron | DRUGTECH CORPORATION | 2006-06-22 | — | — | US | claimed |
| WO-2003086321-A2 | MODIFIED RELEASE MINERALS | DRUGTECH CORPORATION (US) | 2003-10-23 | — | — | WO | claimed |
| US-20030190355-A1 | Modified release minerals | DRUGTECH CORPORATION | 2003-10-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122705-A1 | IRON AMINO ACID COMPOUNDS, METHOD FOR PREPARING IRON AMINO ACID COMPOUNDS, COMPOSITIONS CONTAINING IRON AMINO ACID COMPOUNDS, AND USES THEREOF | HAMP, FECH, TFRC | CA4 1390/4885CTSL 3461/4885CPT2 1273/4885 |
| US-20180370903-A1 | IRON AMINO ACID COMPOUNDS, METHOD FOR PREPARING IRON AMINO ACID COMPOUNDS, COMPOSITIONS CONTAINING IRON AMINO ACID COMPOUNDS, AND USES THEREOF | HAMP, FECH, TFRC | CA4 1390/4885CTSL 3461/4885CPT2 1273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.